Workshop on Pyrogen Testing Methods September 18-19
NICEATM is co-organizing a workshop on September 18-19 with the PETA International Science Consortium to discuss non-animal approaches for pyrogen testing. The workshop will be held at NIH in Bethesda, Maryland, and will focus on the use of the monocyte activation test (MAT) as a standalone release test for medical devices. Registration and materials will be posted on the NICEATM website when available.
Pyrogens are substances such as bacteria, fungi, and viruses that can produce fever. Medical products for implantation or injection must be shown to be free of pyrogens before use. This workshop will bring together scientists and regulatory authorities from government and industry to review the MAT and discuss ongoing challenges such as identifying material-mediated and other non-endotoxin pyrogens. Participants will also describe industry experience and use of the MAT and identify any issues to be addressed to enable its implementation.