Public consultation on Threshold of Toxicological Concern (TTC) Approach; deadline April 12

Author: Sherry Ward, AltTox

“The Threshold of Toxicological Concern (TTC) is a methodology that may be used to assess potential human health concerns for a chemical based on its chemical characteristics and estimated exposure when chemical-specific toxicity data are scarce or absent. Overall, the TTC approach integrates data on exposure, chemical structure, metabolism, and toxicity consistent with standard risk assessment principles” (http://www.efsa.europa.eu/en/consultations/call/150212.pdf).

The EFSA/WHO Working Group is seeking public input on their draft conclusions and recommendations on the use of TTC: http://www.efsa.europa.eu/en/consultations/call/150212.htm?utm_source=newsletter&utm_medium=email&utm_content=call&utm_campaign=20150327

“The overall goal of the project is to develop a globally harmonised decision tree for a tiered approach to the application of TTC in the risk assessment of chemicals.”

The deadline for submitting comments has been extended to April 12, 2015.