Integrated Chemical Environment Adds Formulations Viewer
A recent update to the NICEATM Integrated Chemical Environment (ICE) added a formulations viewer that allows users to explore toxicity data on formulations and their active ingredients. ICE currently includes data for about 700 formulations from six-pack studies for pesticide registration: acute oral, dermal, and inhalation toxicity; skin sensitization; and skin and eye irritation. Active ingredient lists from a formulations query can be used to query the ICE Integrator for data on these substances from other in vivo and in vitro assays.
The recent ICE update also added updated and expanded physicochemical property predictions, updated androgen and estrogen pathway model predictions, and improved filtering on assay endpoints. Additional updates planned for the near future include interactive workflows for prediction of physicochemical property data; chemical use category information; and in vitro to in vivo extrapolation predictions using ICE data.