Catherine Sprankle, NICEATM The focus of the September 27 meeting of the Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) will be topics related to the development of a U.S. strategy and roadmap for implementing 21st century toxicity testing approaches. Background material and specific questions to be discussed by SACATM are included in an “In […]
Catherine Sprankle, NICEATM The National Toxicology Program Interagency Center for the Evaluation of Alternative Methods (NICEATM) encourages U.S. small businesses involved in alternative methods development to apply for Small Business Innovation Research (SBIR) Phase IIB Awards for Validation and Commercialization of Approaches to Reduce Animal Use in Toxicology Testing offered by the National Institute of […]
Catherine Sprankle, NICEATM The National Center for Advancing Translational Sciences (NCATS) and the Center for the Advancement of Science in Space are promoting a new program for research on the International Space Station United States National Laboratory (ISS-NL): we’re sending tissue chips to space! This program will leverage recent advances in tissue engineering and microfabrication […]
Catherine Willet, HSUS OECD has created a new web page to list Adverse Outcome Pathways that have undergone scientific review by experts and have been agreed by the OECD National Coordinators to represent the current state of knowledge: Four of the first five AOPs to have undergone this review are now posted: Adverse Outcome Pathway […]
Sherry Ward, AltTox “The National Institutes of Health (NIH) is requesting public comment on a proposal to amend Section IV and Section V of the NIH Guidelines for Human Stem Cell Research, and on the proposed scope of certain human-animal chimera research that will be considered internally by an NIH steering committee to provide programmatic […]
Posted: August 25, 2016 In 2007 the National Research Council (NRC) published the seminal report, Toxicity Testing in the 21st Century: A Vision and a Strategy, which envisioned using information derived from human-based assays and models to provide a more efficient, predictive, and less costly system for assessing the effects of xenobiotics on human health. […]
Sherry Ward, AltTox The 2016 CRACK IT Challenges competition consists of the following four Challenges: Maximise: “To develop reliable predictions which confidently classify mixtures of chemicals for acute oral toxicity, skin and eye irritation with a focus on relevance for human safety. These should fulfill acute GHS Classification and Labeling requirements for non-encapsulated agrochemical mixtures […]
Sherry Ward, AltTox The Institute for In Vitro Sciences, Inc. (IIVS) is pleased to be among the projects and scientists that have made the shortlist for the 2016 LUSH Prize. Awarded by LUSH, the maker of fresh handmade cosmetics, the annual £250,000 prize recognizes achievements in the non-animal testing sector in five main categories: Lobbying, […]
Catherine Sprankle, NICEATM The ICCVAM 2014-2015 Biennial Progress Report is now available on the National Toxicology Program website. This report, prepared in accordance with requirements of the ICCVAM Authorization Act of 2000 (42 U.S.C. 285l-3), describes ICCVAM and ICCVAM agency activities from January 2014 through December 2015. Key ICCVAM, ICCVAM agency, and NICEATM accomplishments summarized […]
Catherine Sprankle, NICEATM NICEATM and the PETA International Science Consortium (PISC) are co-hosting a webinar series on Alternative Approaches for Acute Inhalation Toxicity to Address Global Regulatory and Non-regulatory Data Requirements. The last webinar in the series will be Thursday, September 8, from 11:00 a.m. to 12:30 p.m. EDT. Dan Huh, Ph.D., University of Pennsylvania, […]
Catherine Sprankle, NICEATM An August 2015 workshop sponsored by the National Institute of Environmental Health Sciences evaluated the scientific support for the Low-Dose Mixture Hypothesis of Carcinogenesis and developed a research agenda. A report from this workshop is now available on the Environmental Health Perspectives website. NICEATM Deputy Director Nicole Kleinstreuer, Ph.D., was a breakout […]
Catherine Willet, HSUS Unilever has launched an award to promote development and application of alternatives in China. The award called “Chinese Society of Toxicology Toxicology Unilever Alternatives Awards” was set up by Chinese society of toxicology, funded by Unilever. Two types of awards were announced: “Chinese Society of Toxicology Toxicology alternatives Unilever Innovation Award” (3 winners) and the “Chinese Society of Toxicology […]
Catherine Sprankle, NICEATM In its Sunday, August 7, edition, The Raleigh News and Observer named NICEATM Director Warren Casey, Ph.D., as its “Tar Heel of the Week.” The newspaper’s weekly feature recognizes North Carolinians who have made important contributions to their areas of interest or expertise. The article noted that Casey, recipient of this year’s […]
Catherine Sprankle, NICEATM In a July 18 Federal Register notice, NICEATM requested data and information on approaches and technologies currently used to identify substances with the potential to cause acute systemic toxicity when swallowed, inhaled, or absorbed through the skin. Respondents should provide information on any activities relevant to the development or validation of alternatives […]
Sherry Ward, AltTox There are two remaining webinars in ACI series on Chemical-induced Asthma: August 26th 11 a.m. Eastern Time Scott Dotson (NIOSH) – Asthma Risk Assessment: A Regulatory Perspective October 21st 11 a.m. Eastern Time Andrew Maier (University of Cincinnati) – Asthma-specific Hazard Characterization Approaches: A Novel Approach to a Complex Problem
Kate Willett, HSUS The OECD has published a Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests. From the introduction: The OECD Guidelines for the Testing of Chemicals are continually evolving to reflect changing assessment practices. Acute toxicity tests are an area of focus for developing alternative assays to address animal […]
