Upcoming calls for proposals

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Upcoming calls for proposals

Sherry Ward, AltTox

Engineering Next-Generation Human Nervous System Microphysiological Systems (R21) (PAR-16-397) and (R01) (PAR-16-398) Application Receipt/Submission Date(s): Standard dates apply through January 8, 2020

This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) with improved fidelity to complex human brain, spinal, peripheral nervous system and/or sensory end organ circuit physiology in vivo, which will ultimately facilitate analysis of higher order functional deficits relevant to complex nervous system disorders.

Revolutionizing Innovative, Visionary Environmental Health Research (RIVER) (R35) (RFA-ES-16-008) Application Receipt Date(s): October 24, 2016

The NIEHS Revolutionizing Innovative, Visionary Environmental health Research (RIVER) program seeks to provide support for the majority of the independent research program for outstanding investigators in the Environmental Health Sciences, giving them intellectual and administrative freedom, as well as sustained support to pursue their research in novel directions in order to achieve greater impacts.  The program seeks to identify individuals, regardless of career stage, with a track record of innovative and impactful research and combine their existing investigator-initiated research into a single seven year award with direct costs of up to $750,000 based on current NIEHS funding. 

Tools for Cell Line Identification (SBIR [R43/R44]) (PA-16-186) Application Receipt Date(s): Standard dates through April 6, 2019

This Funding Opportunity Announcement (FOA) is intended to address the problem of misidentified cell lines. Many advances in biomedical science have arisen from studies of cultured cell lines, which are widely used for basic research on cell function, as models for disease, and for drug screening. However, cell cultures are prone to contamination by foreign cells, which may rapidly displace the original cells. The identity of cultured cells should be routinely verified, but a majority of laboratories do not monitor the identity of their cell lines, and many cell lines are misidentified. The costs, effort and time required to confirm the identity of cell lines has been a barrier to adoption of cell line identification as a routine quality control measure. This FOA will support SBIR projects to improve existing technologies, and/or develop novel, reliable, and cost effective tools that will make it easier for researchers to confirm the identity and/or sex of the cells that they use in their work.

Development of Assays for High-Throughput Screening for Use in Probe and Pre-therapeutic Discovery (R01) (PAR-13-364) Application Submission Date(s): Standard dates apply through January 8, 2017

Through this FOA, NIH wishes to stimulate research in 1) developing assays for specific biological targets and disease mechanisms relevant to the mission of participating NIH Institutes with the intent to screen for small molecule compounds that show potential as probes for use in advancing knowledge about the known targets, identifying new targets, or as pre-therapeutic leads; and 2) establishing collaboration with screening centers that have the requisite expertise and experience needed in implementation of HTS assays for the discovery and development of small molecule chemical probes. This FOA seeks to establish a stream of scientifically and technologically outstanding assays for screening by the NIH Molecular Libraries Production Centers Network (MLPCN) in the Molecular Libraries Program (MLP) and other academic centers. One important criterion for this initiative is novelty.