Tim Shafer received a B.S. in Biology and Chemistry from Hope College in 1986, and a Ph.D. in Pharmacology and Toxicology at Michigan State University in 1991, where he studied the actions of methylmercury on calcium channel function. Tim joined the Neurotoxicology Division of the U.S. Environmental Protection Agency's National Health and Environmental Effects Research Laboratory as a post-doc in 1991, and was hired as a Principle Investigator in that organization in 1994. In 2009, he became part of the newly created Integrated Systems Toxicology Division. Dr. Shafer's research program has utilized a variety of electrophysiological and biochemical approaches to increase the understanding of mechanisms underlying the neurotoxicity of diverse environmental chemicals including metals, pesticides, solvents and PCBs. Currently, research in his lab is focused on developing in vitro assays that can be utilized to identify potential hazards of large numbers of chemicals and prioritize them for additional testing. More specifically, his research is examining functional approaches, such as microelectrode arrays, that can be used to detect potential neurotoxicants and prioritize them for additional testing.
Timothy J. Shafer, PhD
Integrated Systems Toxicology Division
National Health and Environmental Effects Research Laboratory
U.S. Environmental Protection Agency
Research Triangle Park, NC 27711
MD B105-03
Email: shafer.tim@epa.gov
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