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References


Last Updated: March 31, 2008
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  1. National Research Council (NRC). (2007). Toxicity Testing in the 21st Century: A Vision and A Strategy. National Academy Press, Washington, DC.
  2. Inglese, J., Auld, D.S., Jadhav, A., Johnson, R.L., et al. (2006). Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries. Proc. Natl. Acad. Sci. USA. 103, 11473.
  3. Austin, C.P., Brady, L.S., Insel, T.R. & Collins F.S. (2004). NIH Molecular Libraries Initiative. Science. 306, 1138.
  4. Hoheisel, J.D. (2006). Microarray technology: beyond transcript profiling and genotype analysis. Nat. Rev. Genet. 7, 200.
  5. National Research Council. (2007). Validation of Toxicogenomic Technologies: A Workshop Summary. National Academy Press, Washington, DC.
  6. Aldridge, B.B., Burke, J.M., Lauffenburger, D.A. & Sorger, P.K. (2006). Physicochemical modelling of cell signalling pathways. Nat. Cell Biol. 8, 1195.
  7. Andersen, M.E., Yang, R.S., French, C.T., Chubb, L.S. & Dennison, J.E. (2002). Molecular circuits, biological switches, and nonlinear dose-response relationships. Environ. Health Perspect. 110 (6), 971.
  8. Alon, U. (2006). An Introduction to Systems Biology: Design Principles of Biological Circuits. CRC Press, Boca Raton, FL.
  9. Reddy, M.B. Yang, R.S.H, Clewell III, H.J. & Andersen, M.E., Eds. (2005). Physiologically Based Pharmacokinetics: Science and Application. John Wiley & Sons, Hoboken, NJ.
  10. Blaauboer, B. (2003). The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary. Toxicol. Lett. 138, 161.
  11. National Research Council. (2006). Human Biomonitoring for Environmental Chemicals. National Academy Press, Washington, DC.
  12. Krewski D., Hogan, V., Turner, M., Zeman, P., et al. (2007). An Integrated Framework for Risk Management and Population Health. Hum. Ecol. Risk Assess. 13, 1288.
  13. Andersen, M.E., Thomas, R.S., Gaido, K.W. & Conolly, R.B. (2005). Dose-response modeling in reproductive toxicology in the systems biology era. Reprod. Toxicol. 19, 327.