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Non-animal Methods for Toxicity Testing

Author Biography: Andersen, et al.

Last Updated: March 31, 2008
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Melvin E. Andersen, PhD, is Director, Institute for Chemical Safety Sciences, The Hamner Institutes for Health Research, Research Triangle Park, NC. Over a 40-year toxicology career, he has worked in the federal government (US Navy, Department of Defense and EPA), private industry (ICF Kaiser) and academia (Colorado State University). He has over 400 published papers and book chapters in a research career focused on computational approaches for dose response modeling and human health risk assessment.  Increasingly, his programs at The Hamner are becoming more closely aligned with accelerating acceptance of toxicity testing approaches outlined by the 2007 NAS report, "Toxicity Testing in the 21st Century: A Vision and A Strategy". He holds a PhD in Biochemistry and Molecular Biology from Cornell.


Melvin E. Andersen, Director
Institute for Chemical Safety Sciences
The Hamner Institutes for Health Sciences
6 Davis Drive
P.O. Box 12137
Research Triangle Park, NC 27709-2137
Email: mandersen@thehamner.org

 

Daniel Krewski is professor of epidemiology and community medicine and director of the McLaughlin Centre for Population Health Risk Assessment at the University of Ottawa. Previously, he served as director of the Bureau of Chemical Hazards and director of risk management at Health Canada. His research interests include epidemiology, biostatistics, risk assessment, and risk management. Dr. Krewski is a member of the National Research Council (NRC) Nuclear and Radiation Studies Board and previously served on its Committee on Health Risks of Exposure to Radon (BEIR VI) and its Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation (BEIR VII, Phase 2). Dr. Krewski also served on the Board on Environmental Studies and Toxicology, the Committee on Research Priorities for Airborne Particulate Matter, the Committee on Grand Challenges in Environmental Science, the Committee on Comparative Toxicity of Naturally Occurring Carcinogens the Committee on Toxicology (COT), the COT Subcommittee on the Health Effects of Ingested Fluoride, and the Subcommittee on Pharmacokinetics in Risk Assessment of the Safe Drinking Water Committee. Dr. Krewski chaired the Committee on Acute Exposure Guideline Levels from 1998 to 2004, and the Colloquium on Scientific Advances and the Future of Toxicologic Risk Assessment held in 1997 on the 50th anniversary of the COT. Dr. Krewski received his MSc and PhD in mathematics and statistics from Carleton University and his MHS from the University of Ottawa.


Dr. Daniel Krewski
Institute of Population Health
1 Stewart Street, Room 320
Ottawa, ON K1N 6N5
E-mail: dkrewski@uottawa.ca

 

Lauren Zeise is chief of the Reproductive and Cancer Hazard Assessment Branch of the California Environmental Protection Agency. Dr. Zeise's research focuses on modeling human interindividual variability and risk. She has served on advisory boards of the US Environmental Protection Agency (EPA), the World Health Organization, the Office of Technology and Assessment, and the National Institute of Environmental Health Sciences. She has also served on several National Research Council committees, including the Committee on Risk Characterization, the Committee on Comparative Toxicology of Naturally Occurring Carcinogens, the Committee on Copper in Drinking water, and the Committee to Review EPA's Research Grants Program. Dr. Zeise is a member of the Board on Environmental Studies and Toxicology. She received her PhD from Harvard University.


Dr. Lauren Zeise
California Environmental Protection Agency
Oakland Office
1515 Clay Street, 16th floor
Oakland, CA 94612
Email: lzeise@oehha.ca.gov