AltTox.org

Non-animal Methods for Toxicity Testing

Additional Resources for Non-animal Toxicity Test Methods


Last Updated: April 1, 2010
Print |
Email

ALTEX article Alternatives to Animal Experimentation in Basic Research (2004): http://www.altex.ch/resources/gruberhartung_suppl_2004.pdf

AltTox Toxicity Testing Resource Center: http://alttox.org/ttrc/

AltWeb Search for Alternatives: http://altweb.jhsph.edu/resources/searchalt/index.html

Canadian Council on Animal Care (CCAC) 3Rs Search Guide: http://searchguide.ccac.ca/

CCAC Alternative Test Methods Table: Validation & Regulatory Status: http://www.ccac.ca/en/alternatives/ATM-table-MRE/intro.html

Critical Reviews in Toxicology article by Creton, et al. (2010) explains opportunities to waive requirements for acute toxicity testing of chemicals or using alternative approaches. Available at: http://www.nc3rs.org.uk/news.asp?id=1252

DB-ALM ECVAM Database Service on Alternative Methods to Animal Experimentation: http://ecvam-dbalm.jrc.ec.europa.eu

Defra (UK Department for Environment, Food and Rural Affairs) updated guidance for minimizing animal testing for REACH: http://www.defra.gov.uk/environment/quality/chemicals/reach/documents/reach-animal-testing-article.pdf

European Centre for the Validation of Alternative Methods (ECVAM): http://ecvam.jrc.ec.europa.eu/index.htm

Fund for the Replacement of Animals in Medical Experiments (FRAME). A Guide to Searching for Alternatives to the Use of Laboratory Animals: http://www.frame.org.uk/page.php?pg_id=139

Go3R semantic search to avoid animal experiments: http://www.go3r.org/

Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): http://iccvam.niehs.nih.gov

INVITTOX list of protocols for in vitro techniques: see DB-ALM ECVAM Database for current list of protocols

Japanese Center for the Validation of Alternative Methods (JaCVAM): http://jacvam.jp/en/index.html

National Institutes of Health. Searching for Alternatives to Painful Procedures Used on Research Animals: http://nihlibrary.ors.nih.gov/training/AlternativesSearchTipSheet5-24-04.pdf

National Library of Medicine (NLM), ALTBIB and PubMed. Bibliography on Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing: http://toxnet.nlm.nih.gov/altbib.html

NLM TOXNET databases: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?index.html

NC3Rs Information Portal: http://www.nc3rs.org.uk/landing.asp?id=38

Organisation for Economic Co-operation and Development (OECD) Guidance & Review Documents: http://www.oecd.org/document/30/0,2340,en_2649_34365_1916638_1_1_1_1,00.html

OECD Series on Testing and Assessment / Adopted Guidance and Review Documents: http://www.oecd.org/document/30/0,3343,en_2649_34377_1916638_1_1_1_1,00.html

OECD Draft Test Guidelines: http://www.oecd.org/document/55/0,3343,en_2649_34373_2349687_1_1_1_1,00.html

TSAR: Tracking System for Alternative test methods Review, Validation and Approval in the Context of EU Regulations on Chemicals: http://tsar.jrc.ec.europa.eu/

UCDavis Center for Animal Alternatives Information, Literature Search for Alternatives Worksheet: http://www.lib.ucdavis.edu/dept/animalalternatives/worksheet.php

UK Health and Safety Executive (HSE) and UK REACH Competent Authority guidance on strategies for reducing animal testing for REACH: http://www.hse.gov.uk/reach/resources/18animaltesting.pdf

USDA Animal Welfare Information Center Bulletin (AWIC) Bulletin, Vol. 13, No. 3, Summer 2008. The Use of Databases, Information Centers and Guidelines When Planning Research That May Involve Animals. Available at:  http://www.nal.usda.gov/awic/newsletters/v13n3/AWICBulletinV13N3.pdf

USDA AWIC Bulletin, Vol. 12, No. 3-4, Summer 2006. Searching Bibliographic Databases for Alternatives. Available at:  http://www.nal.usda.gov/awic/newsletters/v12n3/V12N34final2.pdf

ZEBET(Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments, Germany). AnimAlt-ZEBET database: https://gripsdb.dimdi.de/websearch/servlet/Gate?accessid=bfrAnimaltBasicEn#__DEFANCHOR