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Non-animal Methods for Toxicity Testing

References


Last Updated: December 6, 2007
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Di Ventura, B., Lemerle, C., Michalodimitrakis, K., & Serrano, L. (2006). From in vivo to in silico biology and back. Nature. 443(5), 527-533.

Dix, D.J., Houck, K.A., Martin, M.T., Richard, A.M., Setzer, R.W. & Kavlock, R.J. (2007). The ToxCast program for prioritizing toxicity testing of environmental chemicals. Toxicol. Sci. (Forum), 95, 5-12.

Houck, K. & Kavlock, R.J. (2007). Understanding Mechanisms of Toxicity: Insights from Drug Discovery. Toxicol. Appl. Pharm. (in press).

Kavlock, R., Ankley, G.T., Collette, T., Francis, E., Hammerstrom, K., Fowle, J., Tilson, H., Toth, G., Schmieder, P., Veith, G.D., Weber, E., Wolf, D.C. & Young, D. (2005). Computational toxicology: framework, partnerships, and program development. Reprod. Toxicol. 19, 265-280.

Inglese, J., Auld, D.S., Jadhav, A., Johnson, R.L., Simeonov, A., Yasgar, A., Zheng, W. & Austin, C.P. (2006). Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries. Proc. Natl. Acad. Sci. USA. 103, 11473-11478.

Richard, A. (2006). The Future of Toxicology – Predictive Toxicology: An Expanded View of "Chemical Toxicity." Chemical Research In Toxicology. 19(10), 1257-1261.

National Research Council. (2007). Toxicity Testing in the Twenty-first Century: A Vision and a Strategy. The National Academies Press, Washington, DC.