Archives

Tag Archives for: "toxicity testing"
Home / toxicity testing

In the Spotlight

Posted in In the Spotlight on

Implementing the Vision for Toxicity Testing in the 21st Century: An Opportunity for Action

Posted: August 25, 2016 In 2007 the National Research Council (NRC) published the seminal report, Toxicity Testing in the 21st Century: A Vision and a Strategy, which envisioned using information derived from human-based assays and models to provide a more efficient, predictive, and less costly system for assessing the effects of xenobiotics on human health. […]
0Read More
Posted in In the Spotlight on

A host of new and revised OECD test guidelines feature in vitro methods

The Organisation for Economic Co-operation and Development (OECD) establishes guidance for commerce and trade between its 34 member countries, which include countries in Europe, the United States, Canada, Mexico, Australia, New Zealand, Japan, and South Korea, with Brazil, India, Indonesia, the People’s Republic of China and South Africa participating as Key Partners. Guidance for assessing […]
2Read More
Posted in In the Spotlight on

Public forum highlights progress on replacing animals used in safety testing

Reprinted from Environmental Factor, July 2015, with permission. Members of the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) discussed alternatives for chemical and product safety testing during a May 27 public forum at the National Institutes of Health in Bethesda, Maryland. Participants discussed subjects such as transparency in industry’s reporting of animal […]
0Read More
Posted in Journal Watch on

Predicting drug-induced liver injury with micro-patterned co-cultured IPSC-derived human hepatocytes

Researchers from Colorado State University used an enhanced process for creating human hepatocyte-like cells derived from induced pluripotent stem cells (iPSC-HH) to produce hepatocytes with a more consistent phenotype and longer life span than previous methods have yielded. In a new paper in Toxicological Sciences, the team describes the ability of these new cells to […]
0Read More
Posted in In the Spotlight on

Novel technologies to overcome challenges faced by the pharmaceutical and chemical industries

Industry, small and medium-sized enterprises and academia are coming together, through the NC3Rs CRACK IT program, to solve three challenges faced by the pharmaceutical and chemical industries; all of which should reduce the number of animals used in scientific research. Nine research and development consortia have been awarded up to £100,000 each, as part of […]
0Read More
Posted in Journal Watch on

“Regulatory acceptance and use of the Extended One Generation Reproductive Toxicity Study within Europe”

In this paper published recently in Regulatory Toxicology and Pharmacology, Marie-Jeanne W.A. Schiffelers and co-authors reconstruct and analyze the process of regulatory acceptance and use of the Extended One Generation Reproductive Toxicity Study as a replacement for the two generation study. (Disclosure: AltTox Management Team member Bas J. Blaauboer is one of the co-authors on […]
0Read More
Posted in In the Spotlight on

IFER funds new graduate fellowships for research into the development of alternatives to the use of animals in science

Posted: October 15, 2014 Peggy Cunniff, President of the International Foundation for Ethical Research (IFER), and Peter O’Donovan, Executive Director of IFER, announced this week the funding of three new graduate fellowships, and the renewal of three fellowships awarded in previous years. The awards are based on recommendations of the IFER Scientific Advisory Board following […]
0Read More