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EURL ECVAM report on alternative methods

Contributor: Kristie Sullivan, PCRM The European Union Reference Laboratory for alternatives to animal testing (EURL ECVAM) has published an extremely comprehensive report on all its activities related to human and ecological health, the development and validation of alternative methods, and information dissemination, and regulatory implementation. The report contains summaries of, e.g., EURL ECVAM’s activities in […]
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Links to recently published OECD in vitro test guidelines

Contributor: Kate Willett, HSUS Here are links to four recently published OECD in vitro test guidelines: Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene http://www.oecd-ilibrary.org/environment/test-no-490-in-vitro-mammalian-cell-gene-mutation-tests-using-the-thymidine-kinase-gene_9789264242241-en;jsessionid=22dh652p3oaq6.x-oecd-live-02 Test No. 491: Short Time Exposure In Vitro Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring […]
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Posted in In the Spotlight on

A host of new and revised OECD test guidelines feature in vitro methods

The Organisation for Economic Co-operation and Development (OECD) establishes guidance for commerce and trade between its 34 member countries, which include countries in Europe, the United States, Canada, Mexico, Australia, New Zealand, Japan, and South Korea, with Brazil, India, Indonesia, the People’s Republic of China and South Africa participating as Key Partners. Guidance for assessing […]
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“Regulatory acceptance and use of the Extended One Generation Reproductive Toxicity Study within Europe”

In this paper published recently in Regulatory Toxicology and Pharmacology, Marie-Jeanne W.A. Schiffelers and co-authors reconstruct and analyze the process of regulatory acceptance and use of the Extended One Generation Reproductive Toxicity Study as a replacement for the two generation study. (Disclosure: AltTox Management Team member Bas J. Blaauboer is one of the co-authors on […]
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