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Tracking progress: They say, knowledge is power

Posted: May 31, 2016 One of our content updates this month is an updated version of AltTox’s Table of Validated & Accepted Alternative Methods (“Table”). This Table, which provides a comprehensive list of alternative methods endorsed as scientifically valid by ICCVAM (United States), EURL ECVAM (European Union), and/or JaCVAM (Japan), has become one of the […]
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The Year in Review: AltTox Editorial Board members reflect on significant technology and policy developments in 2015

Posted: December 28, 2015 For the final “In the Spotlight” article of 2015, we asked AltTox Editorial Board members to identify what they saw as the most significant development for non-animal chemical safety testing, in the realms of technology or policy. Here is what some of them had to say. Bas Blaauboer: “An important step […]
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In the US and EU, proposals are advanced to reduce the use of animals for acute systemic toxicity testing

Acute systemic toxicity refers to the adverse reactions that occur within 24 hours of oral or dermal exposure to a substance, or within 4 hours of inhalation exposure. In traditional toxicity testing procedures it is measured by the median lethal dose (LD50 for oral or dermal routes of exposure, or LC50 – median lethal concentration […]
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Links to recently published OECD in vitro test guidelines

Contributor: Kate Willett, HSUS Here are links to four recently published OECD in vitro test guidelines: Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene http://www.oecd-ilibrary.org/environment/test-no-490-in-vitro-mammalian-cell-gene-mutation-tests-using-the-thymidine-kinase-gene_9789264242241-en;jsessionid=22dh652p3oaq6.x-oecd-live-02 Test No. 491: Short Time Exposure In Vitro Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring […]
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