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Journal Watch

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A Scalable, Highly Reproducible Method for Creating 3-D Neural Constructs

In a recent paper in PNAS, Michael P. Schwarz and co-authors describe a method for creating structurally complex, 3D neural constructs for neurotoxicity testing, by co-culturing human embryonic stem cell-derived neural progenitor cells, endothelial cells, mesenchymal cells, and microglia/macrophage precursors. The resulting neural constructs more closely replicate human brain tissue than monocultures or animal-derived cells, […]
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New issue of CSS Pathways from the US EPA

Contributor: Sherry Ward, AltTox The August 2015 issues of CSS Pathways ( reports many developments in chemical safety research and testing by US EPA researchers. Several approaches to assessing potential endocrine disruptors are reported: EPA introduces new technology to screen chemicals for endocrine disruption High-throughput model predicts estrogen receptor activity Advancing methods to evaluate thyroid […]
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