National or regional centers and professional, industrial, academic, or non-governmental organizations involved with developing, using, and/or promoting non-animal alternative methods for toxicity testing.

• United States
• Europe
• Other Regions/International

 United States

Allen Institute for Cell Science

Alternatives Research and Development Foundation (ARDF)

American Society for Cellular and Computational Toxicology (ASCCT)

California Institute for Regenerative Medicine (CIRM)

Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University

Center for Animal Alternatives Information, University of California, Davis

Center for Responsible Science

Environmental Bioinformatics and Computational Toxicology Center (ebCTC): US EPA funded research consortium

Evidence-based Toxicology Collaboration

Global Biological Standards Institute

Harvard Center for Risk Analysis

Human Toxicology Project Consortium

Human Models for Analysis of Pathways Center, Wisconsin Institute for Medical Research (Madison, Wisconsin): U.S. EPA-sponsored Science to Achieve Results center that addresses the need for human, organotypic culture models that comply with the requirements of contemporary toxin screening and drug discovery

In Vitro and Alternative Methods Specialty Section of the Society of Toxicology (IVAM)

Institute for In Vitro Sciences (IIVS)

Interagency Coordinating Committee on the Validation of Alternative Methods/ NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (ICCVAM/NICEATM)

International Foundation for Ethical Research (IFER)

International (Q)SAR Foundation

International Society for Stem Cell Research (ISSCR)

International Society of Regulatory Toxicology & Pharmacology

 National Center for Multiscale Modeling of Biological Systems (MMBioS) (Pittsburgh, PA): develops tools to advance and facilitate cutting-edge research at the interface between high performance computing and the life sciences

Safety Pharmacology Society

Society for In Vitro Biology (SIVB)

Society of Quality Assurance

Society of Toxicology (SOT)

 Europe

3R Research Foundation (Switzerland)

3Rs-Centre Utrecht Life Sciences (The Netherlands)

AP Tox, Portuguese Toxicology Association

Belgian Society of Toxicology and Ecotoxicology (BELTOX)

Biograf 3R: computational alternatives to animal testing

Björn Ekwall Memorial Foundation

Center for Alternatives to Animal Testing – Europe (CAAT-Europe) (Germany)

Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET) Federal Institute for Risk Assessment (BfR) (Germany)

CZECOPA (Czech Republic)

Danish 3R-Center

Danish foundation, Alternativfondet

Danish Society for the Protection of Laboratory Animals (Forsøgsdyrenes Værn)

Doerenkamp-Zbinden Foundation (Switzerland)

Dr Hadwen Trust (UK)

European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM)

European Consensus-Platform for Alternatives (ECOPA)

European Partnership for Alternative Approaches to Animal Testing (EPAA)

European Society for Alternatives to Animal Testing (EUSAAT)

European Society for Animal Cell Technology (ESACT)

European Society of Toxicology In Vitro (ESTIV)

EUROTOX: Federation of European Toxicologists & European Societies of Toxicology

Finnish Centre for Alternative Methods (FICAM)

FINCOPA (Finland)

FRANCOPA (France)

Fund for the Replacement of Animals in Medical Experiments (FRAME)

Innovate UK Non-Animal Technologies Special Interest Group: partnership between NC3Rs and Innovate UK

International Society for In Vitro Methods (INVITROM), previously the Dutch-Belgian Society for In Vitro Methods

In Vitro Testing Industrial Platform (IVTIP)

In Vitro Toxicology Society (IVTS): affiliated with the British Toxicology Society

Italian Platform on Alternative Methods (IPAM) (Italy)

Italian Association for Toxicology In Vitro (CELLTOX)

Laboratory of Mathematical Chemistry (Bulgaria): mathematical methods for predicting toxicity of chemicals and modeling metabolism

Maastrich University, Department of Toxicogenomics

National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) (UK)

The Netherlands More Knowledge with Fewer Animals (MKMD) Program

Norwegian Reference Centre for Laboratory Animal Science & Alternatives (NORECOPA)

Scandinavian Society of Cell Toxicology

SET Foundation (Germany)

Spanish Association of Toxicology, Group on Alternative Methods (GTEMA)

Spanish Network for the Development of Alternative Methods (REMA)

SWECOPA (Sweden)

Swedish Toxicology Sciences Research Center (Swetox)

Swiss Centre for Applied Ecotoxicology

Swiss Centre for Applied Human Toxicology

SYRCLE (SYstematic Review Centre for Laboratory animal Experimentation)

Tissue and Cell Engineering Society (TCES)

Tissue Engineering and Regenerative Medicine International Society, European Chapter (TERMIS-EU)

 Other Regions/International

Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART)

ANZCCART, Animal Ethics Infolink (Australia)

Brazilian Centre for the Validation of Alternative Methods (BraCVAM)

Canadian Council on Animal Care (CCAC)

Cell Stress Society International

Inter-Organization Programme for the Sound Management of Chemicals (IOMC)

International Alliance for Biological Standardization (IABS)

International Council on Animal Protection in OECD Programmes (ICAPO)

International Human Epigenome Consortium (IHEC)

International Life Sciences Institute (ILSI)

International Neurotoxicology Association (INA)

International Society for Computational Biology (ISCB)

International Society for Computational Biology (ISCB) Student Council

 International Union of Toxicology (IUTOX)

Japanese Association for Animal Cell Technology (JAACT)

Japanese Center for the Validation of Alternative Methods (JaCVAM)

Japanese Society for Alternatives to Animal Experiments (JSAAE)

Korean Center for the Validation of Alternative Methods (KoCVAM)

Korean Society for Alternative to Animal Experiments (KSAAE)

Medical Advances Without Animals Trust (MAWA) (Australia)

Replace Animals in Australian Testing (University of Wollongong, Australia)

WHO Chemical Risk Assessment Network