Report Outlines Predictive Toxicology Approach for Defense Applications

Contributor: Catherine Sprankle, NICEATM

The National Academies Press has issued a report on “Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense.” Prepared in response to a request by the U.S. Department of Defense, the report provides a conceptual approach that could be used to evaluate chemicals that could pose threats to deployed personnel. In addition to providing an overview of current computational and high-throughput testing approaches and methods for integrating data and predictions, the report summarizes lessons learned from current high-throughput screening programs and suggests initial steps for investment. The report can be read online or downloaded as a PDF for free.