Report Available from Rabies Vaccine Workshop

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Report Available from Rabies Vaccine Workshop

A report is available from the October 2018 workshop “Implementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and Beyond.” NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) Director Warren Casey and David Allen, ILS (contractor supporting NICEATM), workshop participants, coauthored the report.

This workshop, co-sponsored by NICEATM and the International Alliance for Biological Standardization-North America, explored how to advance alternative methods for human and veterinary rabies virus vaccine potency testing. The workshop attendees agreed that a more suitable, scientifically based in vitro assay is needed as an alternative to the current in vivo challenge potency test. ELISA assays specific for rabies virus glycoprotein were identified as the most appropriate in vitro alternative test candidates for further development.

Catherine Sprankle
Catherine Sprankle
Communications Specialist for NICEATM