Recent articles from ECHA explain approaches to minimize animal testing for REACH

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Recent articles from ECHA explain approaches to minimize animal testing for REACH

Author: Sherry Ward, AltTox

The February and April 2015 ECHA Newsletters as well as other recent articles on the ECHA website include information that could assist companies in minimizing animal testing for REACH reporting requirements. In a November 2014 AltTox article (http://alttox.org/cosmetics-regulation-animal-test-ban-declared-subordinate-reach-registration-testing-requirements-echa/), we had cited a statement from the October 2014 ECHA Newsletter that said ECHA is “updating its guidance on information requirements with in vitro methods,” and assume these articles could be part of that initiative.

Some recent ECHA newsletter and website articles that may be of interest are the following:

New toolbox to find safer chemicals and alternative test methods: http://newsletter.echa.europa.eu/home/-/newsletter/entry/2_15_new-toolbox-to-find-safer-chemicals-and-alternative-test-methods  This article explains possible uses of OECD’s Substitution and Alternatives Assessment Toolbox (http://www.oecdsaatoolbox.org/) that was released in January 2015.

Changes on reproductive toxicity tests – are you affected?: http://newsletter.echa.europa.eu/home/-/newsletter/entry/2_15_changes-on-reproductive-toxicity-tests-are-you-affected  “The REACH information requirement for reproductive toxicity was recently amended by the European Commission. It replaced the two-generation reproduction toxicity test with the extended one-generation reproductive toxicity study (EOGRTS). You need to check that the information in your registration dossier complies with the new requirement.”

QSAR Toolbox – the smart way to fill your data gaps: http://newsletter.echa.europa.eu/home/-/newsletter/entry/1_15_qsar-toolbox-the-smart-way-to-fill-your-data-gaps  “A new version of the QSAR Toolbox was launched in December 2014. Are you making full use of it? Companies and authorities are increasingly using it to group chemicals into categories and to fill data gaps by read-across or trend analysis – thereby avoiding the need to test substances on animals, and saving money. You can use the wealth of data in the Toolbox completely free of charge.”

Assessing read-across – how ECHA does it: http://echa.europa.eu/view-article/-/journal_content/title/assessing-read-across-how-echa-does-it

Advice for registrants on skin sensitisation testing helps reduce animal tests: http://echa.europa.eu/view-article/-/journal_content/title/advice-for-registrants-on-skin-sensitisation-testing-helps-reduce-animal-tests

New consumer exposure example helps companies to comply with REACH: http://echa.europa.eu/view-article/-/journal_content/title/new-consumer-exposure-example-helps-companies-to-comply-with-reach

How to address the information requirement on pre-natal developmental toxicity: http://echa.europa.eu/view-article/-/journal_content/title/how-to-address-the-information-requirement-on-pre-natal-developmental-toxicity