New OECD Guidance Document 211 for “non-guideline in vitro test methods“

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New OECD Guidance Document 211 for “non-guideline in vitro test methods“

Author: Horst Spielmann, Free University Berlin, Professor for Regulstory Toxicology & retired from ZEBET at the Federal Institute for Risk Assessment

The following Environment, Health and Safety publication is now available from the Series on Testing and Assessment
Title: Guidance document for describing non-guideline in vitro test methods (No.211)
http://www.oecd.org/chemicalsafety/testing/seriesontestingandassessmentpublicationsbynumber.htm

This guidance document is intended to harmonise the way non-guideline in vitro test methods are described. This should in future facilitate an assessment of the relevance of test methods for biological activities and responses of interest, of the quality of data produced, irrespective of whether these tests are based on manual protocols or assay protocols adapted for use on automated platforms or high-throughput screening systems (HTS). This guidance outlines the elements considered relevant for providing a comprehensive description of an in vitro method to facilitate the interpretation of results and support scientifically defensible fit-for-purpose applications, so as to be suitable for their use in decision making processes by regulators in particular or by the scientific community and end users in general.