IVIVE Workshop Report Available

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IVIVE Workshop Report Available

A manuscript summarizing a February 2016 workshop, In Vitro to In Vivo Extrapolation for High Throughput Prioritization and Decision Making, and a preceding webinar series was published online December 5 by the journal Toxicology In Vitro. The manuscript is available on the journal’s website.

The workshop report discusses activities and resources that promote inclusion of in vitro to in vivo extrapolation (IVIVE) in regulatory decision-making. It considers properties of models that successfully generate predictions of in vivo doses from effective in vitro concentration, areas of success, and areas for improvement to reduce model uncertainty. Finally, the report provides case studies on the uses of IVIVE in safety assessments.

Materials from the workshop, which was co-organized by NICEATM and the U.S. Environmental Protection Agency (EPA) National Center for Computational Toxicology, are available on the NICEATM website.

Catherine Sprankle
Catherine Sprankle

Communications Specialist for NICEATM

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