ICCVAM 2014-2015 Biennial Progress Report Now Available

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ICCVAM 2014-2015 Biennial Progress Report Now Available

Catherine Sprankle, NICEATM

The ICCVAM 2014-2015 Biennial Progress Report is now available on the National Toxicology Program website. This report, prepared in accordance with requirements of the ICCVAM Authorization Act of 2000 (42 U.S.C. 285l-3), describes ICCVAM and ICCVAM agency activities from January 2014 through December 2015.

Key ICCVAM, ICCVAM agency, and NICEATM accomplishments summarized in the report include:

  • A computational approach developed by ICCVAM that integrates several types of data to predict human skin sensitization hazard without using animals
  • A U.S. Environmental Protection Agency (EPA) plan to adopt high throughput assays and computational models for detecting and measuring estrogen receptor bioactivity as an alternative for three Tier 1 tests, including the uterotrophic assay, currently used in the Endocrine Disruptor Screening Program to assess estrogen receptor activity
  • Establishment of the ICCVAM Communities of Practice webinar series
  • A NICEATM evaluation of acute oral and dermal toxicity data to determine if oral toxicity tests are sufficient to assign EPA dermal hazard classifications, eliminating the need for separate acute dermal toxicity tests
  • A series of workshops supported by NICEATM and ICCVAM agencies that drafted recommendations on use of an in vitro test with potential to replace animal use for pertussis vaccine testing

Links to this report and all past ICCVAM annual and biennial reports are available on the NICEATM website.

Catherine Sprankle
Catherine Sprankle
Communications Specialist for NICEATM