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Guidance for Community Blog readers and contributors

The AltTox Community Blog replaced the AltTox Forum February 2015. The messages in the archived AltTox Forum, however, are still available for reading.

AltTox.org users are welcome to browse and read Community Blog messages. Only registered users, however, can post messages directly to the blog.

Blog User Agreement for registered users:
  • appropriate content includes scientific and policy news related to in vitro and in silico methods for toxicity testing, meeting announcements, funding information, and other relevant information
  • the Blog is moderated, and messages beyond the scope of AltTox or otherwise inappropriate will be removed
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  • messages posted by external parties express the views of the author, and not necessarily the views of AltTox team members or AltTox sponsors; AltTox does not warrant the accuracy, completeness, or usefulness of any information presented by external parties

Please report offensive or inappropriate content to info@alttox.org

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EU public survey open until March 11: “Accelerating progress in the Replacement, Reduction and Refinement of animal testing through better knowledge sharing”

Contributor: Sherry Ward, AltTox Source: https://eurl-ecvam.jrc.ec.europa.eu/alternatives-to-animal-testing-eu-public-survey-launched Following the European Commission’s Communication published in response to the European Citizens’ Initiative “Stop Vivisection”, the JRC’s Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is conducting a public survey to solicit input from individuals and organisations to identify all types of knowledge sources that might be relevant […]
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Job opening: Director, National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

Contributor: Myra Westmoreland, NIEHS National Institute of Environmental Health Sciences (NIEHS) is seeking a dynamic, highly motivated Senior Scientist to serve as NICEATM Director. NICEATM is the primary federal resource for the development, validation, and evaluation of new toxicological testing methods that reduce, refine, or replace the use of animals (“alternative methods”). NICEATM provides scientific […]
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IVIVE Workshop: Registration and Abstract Submission Closes February 5

Contributor: Catherine Sprankle, NICEATM Friday, February 5, is the deadline for registration and abstract submissions for the workshop on In Vitro to In Vivo Extrapolation for High Throughput Prioritization and Decision Making. The workshop, organized by NICEATM and the U.S. Environmental Protection Agency (EPA), will take place Feb. 17-18 at EPA in Research Triangle Park, […]
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IVAM webinar recordings now available: Using IATA to Facilitate Regulatory Use of Non-Standard Testing Methods

Contributor: Marilyn Matevia, HSUS A recording of the January 27 SOT In Vitro and Alternative Methods Specialty Section webinar, “Use of Integrated Approaches to Testing and Assessment (IATA) To Facilitate Regulatory Use of Non-Standard Testing Methods,” is now available here. The webinar featured two presentations: Introduction to the concept of Adverse Outcome Pathways and IATA […]
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NICEATM Scientists Receive NIEHS Merit Award

Contributor: Catherine Sprankle, NICEATM NICEATM Director Warren Casey, Ph.D., and nine current or former members of the ILS NICEATM contract support team have been named to receive a Merit Award from the National Institute of Environmental Health Sciences (NIEHS). The Merit Award is the highest level honor award given by the NIEHS director and recognizes […]
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Deadlines February 5 for IVIVE Workshop

Contributor: Catherine Sprankle, NICEATM Registration and abstract submission for the Feb. 17-18 workshop on In Vitro to In Vivo Extrapolation for High Throughput Prioritization and Decision Making is open until February 5. Information about the workshop, which is being organized by NICEATM and EPA, is available on the NICEATM website. Links to webinars that provided […]
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Jan 27 Webinar on using Integrated Approaches to Testing and Assessment (IATA) To Facilitate Regulatory Use of Non-Standard Testing Methods

Contributor: Marilyn Matevia, HSUS The SOT In Vitro and Alternative Methods Specialty Section will host a webinar on Use of Integrated Approaches to Testing and Assessment (IATA) To Facilitate Regulatory Use of Non-Standard Testing Methods on Wednesday, Jan. 27, at 12:00 p.m. Eastern Time. Catherine Willett, Ph.D., of the Humane Society of the United States […]
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Kleinstreuer Appointed NICEATM Deputy Director

Congratulations to Nicole Kleinstreuer! From: NICEATM News – January 22, 2016 Nicole Kleinstreuer, Ph.D., has been named deputy director of NICEATM. Kleinstreuer most recently worked for ILS, the NICEATM support contractor, where she led the NICEATM computational toxicology group. In her new role as NICEATM deputy director she will continue to lead NICEATM computational toxicology […]
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Job Opening: Science Communications Officer, HSI/HSUS

Contributor: Marilyn Matevia, HSUS The Humane Society family of organizations (The Humane Society of the United States/HSUS and Humane Society International/HSI) is looking for a Science Communications Officer to advance HSI/HSUS global efforts to stimulate a shift in bioscience research and drug discovery toward human biology-based technologies and models for safety, efficacy and human disease; […]
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Federal Agencies Launch the Transform Tox Testing Challenge to Improve Chemical Screening

Contributor: Marilyn Matevia, HSUS Press release from the EPA, announcing a team challenge to “find new ways to incorporate physiological levels of chemical metabolism into HTS assays”: Today, the U.S. Environmental Protection Agency (EPA) and the National Institutes of Health’s (NIH) National Center for Advancing Translational Sciences (NCATS), and NIH’s National Toxicology Program (NTP) within […]
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The Hamner Institutes for Health Sciences has closed

Contributor: Marilyn Matevia, HSUS A news item in the Triangle Business Journal announces that the Hamner Institutes for Health Sciences has closed. The article notes that a local health consulting company, SciMetrika, has acquired the assets of one Hamner division, the Institute for Chemical Safety Sciences (ICSS), and will “house” these in ScitoVation, “a wholly […]
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Annual BioPolicy Summit on Research Reproducibility in Washington, DC, February 9th

Contributor: Sherry Ward, AltTox Source: GBSI Media Alert New Reproducibility2020 initiative will provide framework for action On Tuesday, February 9, at 12:00 noon EST, Global Biological Standards Institute (GBSI) will host its 2016 BioPolicy Summit at the Newseum in Washington, DC. The Summit welcomes premiere life science thought leaders as speakers, panelists, and guests who will focus on […]
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PCRM Job Opportunity: Director of Research Policy

Contributor: Ashley Felder, PCRM The Physicians Committee for Responsible Medicine is looking for a director with a background in medicine or the life sciences, a passion for animal welfare, and strong leadership and communication skills. The Director of Research Policy will develop and implement strategies to save human and animal lives by replacing the use […]
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AVON Breast Cancer Research Program

Contributor: Sherry Ward, AltTox Letters of Intent for research funding through the AVON Breast Cancer Research Program are due January 7, 2016 for proposals to be submitted later in 2016 (by invitation only). Research priorities Research questions [they] hope to answer to further the development of breast cancer prevention strategies include, but are not limited […]
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NCATS News

Contributor: Sherry Ward, AltTox The National Center for Advancing Translational Sciences (NCATS) is one of 27 Institutes and Centers at the National Institutes of Health (NIH). It was established in 2012 “to transform the translational science process so that new treatments and cures for disease can be delivered to patients faster” (http://www.ncats.nih.gov/about/center). One of the […]
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ICCVAM Webinar on Fundamentals of QSAR and Read-across

Contributor: Catherine Sprankle, NICEATM ICCVAM will present its second Communities of Practice webinar on Jan. 26, 2016, from 1:00-2:30 p.m. The webinar, on “Fundamentals of Using Quantitative Structure–Activity Relationship Models and Read-across Techniques in Predictive Toxicology,” is being organized on behalf of ICCVAM by NICEATM and hosted by the U.S. Environmental Protection Agency’s (EPA’s) National […]
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NICEATM Director Casey Recognized for Contributions to Animal Welfare

Contributor: Catherine Sprankle, NICEATM In a Dec. 14 announcement, the Society of Toxicology (SOT) recognized NICEATM Director Warren Casey, Ph.D., with the 2016 Enhancement of Animal Welfare Award. This award is given for advancing toxicology through the development and application of methods that replace, refine, or reduce the need for experimental animals. In recognizing the […]
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NICEATM and ICCVAM to Hold Forum at SOT

Contributor: Catherine Sprankle, NICEATM NICEATM Director Warren Casey, Ph.D. and ICCVAM Co-chair Anna Lowit, Ph.D. (U.S. Environmental Protection Agency), will lead a discussion forum during the 2016 SOT Annual Meeting. Casey and Lowit will begin the forum with summaries of recent ICCVAM and NICEATM activities, focusing on efforts to reduce animal use for acute systemic […]
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UK “roadmap” to wider use of non-animal technologies

Contributor: Marilyn Matevia, HSUS Six organizations, including NC3Rs, have published a “roadmap” to facilitate the UK’s development and embrace of non-animal technologies, Advancing Predictive Biology. In a recent blog post, NC3Rs Chief Executive Dr. Vicky Robinson provides context to the project: The roadmap is part of a wider collaboration between the six partners which has […]
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Job openings at Silent Spring Institute

Contributor: Kate Willett, HSUS The Silent Spring Institute is looking for research scientists in data science and informatics, chemistry/biochemistry and biomonitoring, and molecular biology or endocrinology. The Institute is seeking candidates for three position postings: a versatile data scientist, machine learning expert, or statistician to tackle big data problems in environmental health and breast cancer […]
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2016 Funding Opportunities

Contributor: Sherry Ward, AltTox (1) Exploratory/Developmental Bioengineering Research Grants (EBRG): http://grants.nih.gov/grants/guide/pa-files/PA-16-040.html Application due dates: March 16, July 16, and November 16, 2016 These awards are open to various types of organizations, including small business. The R21 mechanism supports short-term exploratory research projects. “The purpose of this FOA is to  encourage submission of EBRG applications which […]
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Upcoming workshop: Environment and Health – What’s the Human Microbiome Have to Do With It?

Contributor: Solmaz Spence, National Academies of Sciences, Engineering, and Medicine Workshop Title: The National Academies of Sciences, Engineering, and Medicine’s Emerging Science for Environmental Health Decisions Workshop, Environment and Health: What’s the Human Microbiome Have to Do With It? Date: January 14-15 2016 Location: Washington, D.C., and via webcast The microbiome—the collection of bacteria, viruses […]
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ARDF announces recipients of the 2015 Alternatives Research Grant Program awards

Contributor: Sue A. Leary, Alternatives Research & Development Foundation (ARDF) ARDF is pleased to announce that its 2015 Alternatives Research Grant Program has made its selections. ARDF has awarded $220,000 to scientists developing alternative methods in a variety of areas of medical research, testing, and education. Congratulations to awardees: April Davis, PhD and William Lee, […]
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New paper describes improved method for quantifying electrophiles (potential skin sensitizers)

Contributor: Amar G. Chittiboyina, PhD, National Center for Natural Product Research To add structural information to the existing in chemico methods, an NMR-based method is proposed for probing the reactivity and classification of the potential electrophiles (E) using a model thiol, DCYA. The major advantage of the NMR method is the quantitation of the actual […]
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ASCCT offering student travel awards for the 17th International Conference on QSAR in Environmental and Health Sciences

Contributor: Kristie Sullivan, PCRM The 17th International Conference on QSAR in Environmental and Health Sciences takes place June 13-17, 2016, in Miami Beach, Florida. The abstract deadline is December 4, 2015; early bird registration ends March 1, 2016. Since 1983, this meeting has been an important international gathering in the field of Environmental and Health […]
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CVB Notice 15-13: Alternative approach to hamster potency test for several Leptospira serogroups could reduce animal use by 50%

Contributor: Sherry Ward, AltTox The Center for Veterinary Biologics (CVB) recently added CVB Notice 15-13, Option to Remove Back-titration Hamsters from In Vivo Potency Tests for Leptospira Serogroups Canicola and Icterohaemorrhagiae, to its website: https://www.aphis.usda.gov/animal_health/vet_biologics/publications/notice_15_13.pdf The purpose of this notice is to inform interested parties that the CVB will allow an exemption from the titration […]
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Results from the 2015 GBSI survey on cell line authentication practices

Contributor: Sherry Ward, AltTox AltTox’s May 2015 “In the Spotlight,” Are we inseparable? Reproducible bioassays and authenticated cell lines (http://alttox.org/are-we-inseparable-reproducible-bioassays-and-authenticated-cell-lines-new-initiatives-by-the-global-biological-standards-institute/), asked readers to participate in a survey on cell line authentication practices being conducted by the Global Biological Standards Institute (GBSI). The results are now available! GBSI’s Cell Authentication Survey Shows Little Progress in a […]
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Scientific Job Openings with PETA US and PETA UK

Contributor: Katherine Groff, PETA International Science Consortium Ltd. Multiple scientific positions are available in PETA US and UK offices (check out all of the positions here: http://www.piscltd.org.uk/employment-opportunities-with-peta-us-and-peta-uk), including a Corporate Liaison position in the Regulatory Testing Department with PETA US. The Corporate Liaison will oversee, develop, and carry out PETA’s work with major corporations to […]
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ECHA asks registrants about their consideration of alternative methods

Contributor: Sherry Ward, AltTox Editor’s Note: The AltTox Resource Center page, Searching for Non-animal Toxicity Test Methods, provides links to many sources of information on non-animal test methods: http://alttox.org/resource-center/searching-for-non-animal-toxicity-testing-methods/ ______________________________________ ECHA asks registrants to show how they considered alternative methods before consulting on testing proposals Source: http://echa.europa.eu/view-article/-/journal_content/title/echa-asks-registrants-to-show-how-they-considered-alternative-methods-before-consulting-on-testing-proposals To further ensure that testing on animals is […]
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New publication on non-animal affinity reagents

Contributor: Amy J. Clippinger, PETA International Science Consortium Ltd. There is a growing concern about the lack of quality and reproducibility of animal-derived antibodies, which often show poor specificity or fail to recognize their targets. Time, money, and tens of thousands of animals could be saved, while improving the reproducibility of research, by replacing animal-derived […]
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October 30 Public Meeting on the Coordinated Framework on Biotechnology

Contributor: Sherry Ward, AltTox The Environmental Protection Agency (EPA), Food and Drug Administration (FDA) and United States Department of Agriculture (USDA) will hold a public meeting on October 30, 2015, to discuss the memorandum entitled, “Modernizing the Regulatory System for Biotechnology Products,” issued by the Executive Office of the President on July 2, 2015. The […]
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EPA’s Advancing Systematic Review Workshop (Dec 16-17): Expert/Topic Nominations due November 5

Contributor: Marilyn Matevia, HSUS The US EPA’s National Center for Environmental Assessment (NCEA) is now accepting nominations for experts and topics for its December 16-17 workshop, Advancing Systematic Review for Chemical Risk Assessment. Nominations are due November 5. From the EPA’s meeting announcement: “EPA is developing and implementing a systematic review process within the IRIS […]
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Vacancy: Director, National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)

Contributor: Bonnie Earnhardt, NIH/NIEHS NIEHS is seeking a dynamic, highly motivated Senior Scientist to serve as NICEATM Director.  NICEATM is the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, an office within the Division of the National Toxicology Program.  NICEATM is the primary federal resource for the development, validation, and evaluation of new […]
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Presentations from Acute Toxicity Workshop

Contributor: Catherine Sprankle, NICEATM Presentations from the Sept. 24–25 workshop on Alternative Approaches for Identifying Acute Systemic Toxicity: Moving from Research to Regulatory Testing are now available on the NICEATM website. At this workshop, representatives from regulatory agencies, academia, and industries developed strategies for advancing alternative methods for product safety testing that meet the needs […]
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USDA Issues Guidance on Vaccine Testing

Contributor: Catherine Sprankle, NICEATM The U.S. Department of Agriculture (USDA) Center for Veterinary Biologics (CVB) recently issued CVB Notice 15-13, Option to Remove Back-titration Hamsters from In Vivo Potency Tests for Leptospira Serogroups Canicola and Icterohaemorrhagiae. The notice describes an exemption from the titration requirement in vaccination-challenge potency assays for Leptospira Serogroups Canicola and Icterohaemorrhagiae. […]
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NAS to Examine Low-dose Toxicity

Contributor: Catherine Sprankle, NICEATM A new committee of the National Academy of Sciences (NAS) will examine whether the current toxicity testing practices of the U.S. Environmental Protection Agency adequately consider adverse human health effects of low doses of endocrine-active chemicals. Committee activities will include convening a scientific workshop to support systematic reviews of human and […]
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EURL ECVAM report on alternative methods

Contributor: Kristie Sullivan, PCRM The European Union Reference Laboratory for alternatives to animal testing (EURL ECVAM) has published an extremely comprehensive report on all its activities related to human and ecological health, the development and validation of alternative methods, and information dissemination, and regulatory implementation. The report contains summaries of, e.g., EURL ECVAM’s activities in […]
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Rodent Uterotrophic Database Now Available

Contributor: Catherine Sprankle, NICEATM An article published October 2 as an advance publication in Environmental Health Perspectives describes curation and evaluation of a database of rodent uterotrophic bioactivity. The uterotrophic assay is a widely accepted in vivo test for identifying chemicals with potential estrogen receptor agonist activity. The new database, which includes data from studies […]
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IVIVE Webinars and Workshop

Contributor: Catherine Sprankle, NICEATM A series of four webinars on In Vitro to In Vivo Extrapolation for High Throughput Prioritization and Decision Making are being presented by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and the U.S. Environmental Protection Agency (EPA). The webinar series began October 7 and […]
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New Resource for Small Business Grant Applicants

Contributor: Catherine Sprankle, NICEATM A November 4 webinar will explain how to use the ASSIST (Application Submission System and Interface for Submission Tracking) system for submitting grant applications. ASSIST is an alternative to Grants.gov downloadable forms for applying for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants. Advantages to using ASSIST […]
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Version 2 of S1500+ Human Gene Set Now Available

Contributor: Catherine Sprankle, NICEATM National Institute of Environmental Health Sciences and National Toxicology Program (NTP) scientists along with Tox21 partners have developed a list of environmentally responsive genes to be used in toxicogenomics approaches to screening large numbers of chemicals. Genes on the list were identified through both bioinformatics approaches and experimental data establishing certain […]
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Pre-Applications for Translational Science Awards

Contributor: Catherine Sprankle, NICEATM The NIH invites interested applicants to pre-apply for PAR-15-172 “Collaborative Innovation Award, Clinical and Translational Science Award (CTSA) Program (U01)”. While not required, pre-application for this award is recommended. Applicants submitting pre-applications that are meritorious and programmatically relevant will be notified of the opportunity to submit a full application. NCATS is […]
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EFSA’s 2nd Scientific Conference, October 14-16, can be followed online

Contributor: Sherry Ward, AltTox Registration to this conference is now closed, but you can follow the entire conference online: http://www.efsaexpo2015.eu/join-the-conference-online/ Conference Website: http://www.efsaexpo2015.eu/ Here are descriptions of 3 of the conference sessions: Novel chemical hazard characterization approaches – October 16 from 09:00 to 13:00 Novel tools and testing strategies are revolutionising the way that scientists […]
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EPA’s NCCT is hiring

Contributor: Marilyn Matevia, HSUS An announcement from the EPA: The US Environmental Protection Agency Office of Research Development’s National Center for Computational Toxicology (NCCT) is seeking qualified candidates for four positions 1) Computational Toxicologist, 2) Molecular Toxicologist, 3) Cell Biologist and 4) Text Mining Specialist. Below is more information about the National Center for Computational […]
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International NC3Rs Prize

Contributor: Kristie Sullivan, PCRM From the UK National Centre for the 3Rs Website: “The international NC3Rs Prize is awarded to highlight an outstanding original contribution to scientific and technological advances in the 3Rs in medical, biological or veterinary sciences published within the last three years. The prize is part of our commitment to recognise and […]
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Danish 3R-Center call for project applications to promote the development and implementation of the 3Rs

Contributor: Sherry Ward, AltTox On behalf of The Minister of Environment and Food, The Danish 3R-Center calls for applications to promote the development and implementation of the 3Rs. Call for project applications: http://en.3rcenter.dk/fileadmin/user_upload/images/Forskning/Call_for_project_applications_to_promote_the_development_and_implementation_of_the_3Rs_final.pdf Danish 3R-Center Research Funding: http://en.3rcenter.dk/research-funding/ Application Deadline: Wednesday October 21, 2015. Grants of up to 500.000 DKK can be applied for. Typically, […]
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The AltTox Forum is now the AltTox Community Blog. To search historical postings from the AltTox Forum, visit its original address. For instructions on posting or subscribing, click on the teal box at the top of this page.

The views expressed in the AltTox Community Blog are those of the individuals posting them and not necessarily those of their home institution.