Community Blog

Home / Community Blog

AltTox Community Blog

Blog User Agreement, and instructions for posting or subscribing to the AltTox Community Blog
How to subscribe to the Community Blog

Use the RSS option in the left sidebar, or join the AltTox listserv: send an email to alttox-request@freelists.org, with the word “subscribe” on the subject line, OR visit http://www.freelists.org/list/alttox and sign up directly.

How to post new items to the Community Blog

Please send them to info@alttox.org; include your name and affiliation so that we can credit you as the contributor! If you will be contributing news items frequently and would prefer to post them yourself, please request a new log-in ID and instructions from info@alttox.org.

Guidance for Community Blog readers and contributors

The AltTox Community Blog replaced the AltTox Forum February 2015. The messages in the archived AltTox Forum, however, are still available for reading.

AltTox.org users are welcome to browse and read Community Blog messages. Only registered users, however, can post messages directly to the blog.

Blog User Agreement for registered users:
  • appropriate content includes scientific and policy news related to in vitro and in silico methods for toxicity testing, meeting announcements, funding information, and other relevant information
  • the Blog is moderated, and messages beyond the scope of AltTox or otherwise inappropriate will be removed
  • copyrighted material will not be posted without permission
  • sources of information and related links (when known/available) will be included
  • advertisements are not permitted
  • messages posted by external parties express the views of the author, and not necessarily the views of AltTox team members or AltTox sponsors; AltTox does not warrant the accuracy, completeness, or usefulness of any information presented by external parties

Please report offensive or inappropriate content to info@alttox.org

Posted in Community Blog on

New EPA Guidance for Testing Pesticides Will Reduce Animal Testing

For Release: November 29, 2016 Source: https://www.epa.gov/pesticides/new-epa-guidance-testing-pesticides-will-reduce-animal-testing-0 EPA is issuing guidance for requesting waivers of acute dermal toxicity testing requirements for pesticide formulations, which will lead to fewer animal tests for acute dermal toxicity for pesticides. Last March, EPA released a “Draft Retrospective Analysis for Waiving Acute Dermal Toxicity Tests for Pesticide Formulations,” which included guidance […]
0Read More
Posted in Community Blog on

DB-ALM Updates

DB-ALM updates, November 2016 New Content Since our last communication, 26 new method descriptions of advanced and alternative methods at all stages of development and acceptance have been published. Comprehensive descriptions of novel approach methods with summaries and/or protocols compliant with regulatory guidelines, undergoing scientific validation or developed and evaluated in EU integrated research projects, are […]
0Read More
Posted in Community Blog on

NTP Board of Scientific Counselors Meeting on December 15; comments on ICCVAM strategy due November 30

NTP Board of Scientific Counselors Meeting Date: December 14-15, 2016 Location: Research Triangle Park, North Carolina Register to attend in person or via webcast at: http://ntp.niehs.nih.gov/about/org/bsc/meetings Dr. Warren Casey will present “Strategy for implementing the vision for regulatory toxicity testing in the 21st century” on December 15. Meeting Agenda: http://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2016/december/agenda20161214_508.pdf Written Comments are due by […]
0Read More
Posted in Community Blog on

U.S. EPA TSCA Stakeholder Meeting, December 14, 2016, Washington, DC

Did you see our Tweet below about this important upcoming event? U.S. EPA TSCA Stakeholder Meeting – New Chemicals Program Wednesday, December 14, 2016, 9:00 AM – 12:00 PM EST Ronald Reagan Building and International Trade Center, Washington, DC Event information and registration to attend in person or via webcast are available here: https://www.eventbrite.com/e/us-epa-tsca-stakeholder-meeting-new-chemicals-program-registration-29286083464 EPA […]
0Read More
Posted in Community Blog on

ECHA scientists publish analysis supporting new guidance to reduce acute oral toxicity tests

Sonja von Aulock, ALTEX Scientists from the European Chemicals Agency (ECHA) around Andrea Gissi and Kimmo Louekari have published an analysis of data in the REACH registration database that supports the use of sub-acute toxicity results, together with other relevant information, to cover the acute toxicity standard requirements for REACH registration in a weight of […]
0Read More
Posted in Community Blog on

2016 International Foundation for Ethical Research (IFER) Graduate Fellowship Awards

The International Foundation for Ethical Research (IFER) Board of Directors announced funding for three new Graduate fellowships in October. The new research projects are: T.J. Puls (graduate student) and Dr. Sherry Voytik-Harbin (faculty advisor), Purdue University, Engineering novel 3D tumor-stroma to bridge the gap between preclinical model and human clinical outcomes Danh Truong (graduate student) […]
0Read More
Posted in Community Blog on

Kleinstreuer Receives Lush Cosmetics’ Young Researcher Prize

In a November 2 ceremony, NICEATM Deputy Director Nicole Kleinstreuer received the Lush Cosmetics’ Young Researcher Prize recognizing efforts to eliminate animal use for chemical safety testing. Five researchers in the Americas received the honors presented at Lush Cosmetics headquarters in Vancouver. Kleinstreuer is the first U.S. federal government employee to receive a Lush Prize. […]
0Read More
Posted in Community Blog on

NICEATM Requests Data on Zebrafish Embryo Chemical Screening

NICEATM requests available data and information on zebrafish embryo screening tests and protocol design, including pharmacokinetics measurements. Submitted information will be used to assess the state of the science and determine technical needs for non-animal test methods used to evaluate the potential of chemicals to induce developmental effects in offspring. Respondents to this data request […]
0Read More
Posted in Community Blog on

Resources From the National Library of Medicine: ToxTutor and ALTBIB

The National Library of Medicine has updated its online ToxTutor course. ToxTutor is a self-paced tutorial for users of NLM chemical and toxicology databases that covers the key principles of toxicology. The ToxTutor update incorporates recent advances in the science of toxicology, provides more information on alternatives to animal testing, and features responsive design to […]
0Read More
Posted in Community Blog on

NTP Requests Data on Alternative Methods to Assess Inflammation or Exaggerated Immune Responses

The National Toxicology Program at the National Institute of Environmental Health Sciences requests available data and information on approaches and/or technologies currently used to identify substances with the potential to cause excessive inflammation or exaggerated immune responses leading to tissue injury when swallowed, inhaled, or absorbed through the skin. Submitted information will be used to […]
0Read More
Posted in Community Blog on

Dermal Technology Laboratory received the prestigious Queens’ Award for Enterprise in 2016

“Dermal Technology Laboratory (DTL) has been awarded one of the most coveted accolades in UK business. In recognition of its international growth and success over the past five years. DTL, based at Keele University Science and Innovation Park has received a Queen’s Award for Enterprise.” “Dermal Technology Laboratory specialises in in vitro dermal absorption studies that […]
0Read More
Posted in Community Blog on

Get yours now: ECHA guidance on fulfilling REACH dossiers using alternatives to animal testing

The European Chemicals Agency has published guidance on the use of alternatives to animal testing to fulfill REACH dossier obligations. The Guidance is targeted toward small and medium enterprises (SMEs) and intended to provide guidance in time for the 2o18 deadline. The deadline of 31 May 2018 concerns companies that manufacture or import substances in […]
0Read More
Posted in Community Blog on

Developmental neurotoxicity: OECD/EFSA experts discuss non-animal test methods

Fifty-nine participants from 15 countries attended a workshop on “Developmental Neurotoxicity (DNT): the use of non-animal test methods for regulatory purposes” in Brussels. The event, co-organised by the Organisation for Economic Co-operation and Development (OECD) and the European Food Safety Authority (EFSA), focused on opportunities and challenges related to alternative methods for testing and assessing […]
0Read More
Posted in Community Blog on

NIH funding announcement: Microphysiological Systems for Disease Modeling and Efficacy Testing

Source: http://grants.nih.gov/grants/guide/rfa-files/RFA-TR-16-017.html Title: Microphysiological Systems (MPS) for Disease Modeling and Efficacy Testing (UG3/UH3)  Funding Opportunity Announcement: RFA-TR-16-017 Purpose The purpose of the Microphysiological Systems (MPS) for Disease Modeling and Efficacy Testing Program is to develop highly reproducible and translatable in vitro models for preclinical efficacy studies through discovery and validation of translatable biomarkers, development of […]
0Read More
Posted in Community Blog on

IIVS Releases Training Video to Replace Animals in Phototoxicity Testing

IIVS Releases Training Video to Replace Animals in Testing For Immediate Release Media Contact: Laura Henning 240-454-8459 lhenning@iivs.org GAITHERSBURG, MD – October 12, 2016 – Funded by a grant from the European Partnership for Alternative Approaches to Animal Testing (EPAA), the Institute for In Vitro Sciences, Inc.(IIVS) has released a technical training video that describes […]
0Read More
Posted in Community Blog on

Invitation: Symposium on ‘Phasing out animal experiments, the next steps: applying openness, scientific justification and transparent reporting’

Especially for our European colleagues, notice of an upcoming symposium organized by the newly created Netherlands National Committee for the protection of animals used for scientific purposes (NCad) on December 8, 2016 in Brussels –registration ends Nov 1. From the program description: “The purpose of this symposium is to discuss whether the current animal use […]
0Read More
Posted in Community Blog on

NICEATM and PISC Convene Meeting on Inhalation Alternatives

NICEATM and the PETA International Science Consortium (PISC) organized an expert meeting on “Alternative Approaches for Acute Inhalation Toxicity Testing to Address Global Regulatory and Non-regulatory Data Requirements.” Participants in the meeting, held September 22-23, 2016, in Bethesda, MD, identified four key activities needed to reduce and replace animal use for required inhalation toxicity testing: […]
0Read More
Posted in Community Blog on

Raymond Tice Honored by ARDF

Raymond Tice, former NICEATM Deputy Director and National Toxicology Program (NTP) Biomolecular Screening Branch chief, received the William and Eleanor Cave Award from the Alternatives Research and Development Foundation (ARDF). The William and Eleanor Cave Award is given to recognize contributions to advancing alternatives to the use of animals in testing, research, or education. The […]
0Read More
Posted in Community Blog on

ICCVAM Advisory Committee Discusses Roadmap for Replacing Six Acute Toxicity Tests

The Scientific Advisory Committee for Alternative Toxicological Methods, which advises NICEATM and ICCVAM, met at the National Institute of Environmental Health Sciences in Research Triangle Park, NC, on September 27. ICCVAM agencies outlined a roadmap for the replacement of animals for the six most commonly used acute toxicity tests: ocular and dermal irritation; dermal sensitization; […]
0Read More
Posted in Community Blog on

Many in vitro and in silico approaches encouraged in new funding opportunity from the Bill & Melinda Gates Foundation – Proposals due November 9

Grant Opportunity title: Develop Novel Platforms to Accelerate Contraceptive Drug Discovery (Round 18) Source: http://gcgh.grandchallenges.org/challenge/develop-novel-platforms-accelerate-contraceptive-drug-discovery-round-18 Deadline: 9 Nov 2016 – 11:30am PST The Challenge While access to a range of appropriate and desirable contraceptive methods can have a broad beneficial impact on the lives of women, men and their families, this goal is currently not […]
0Read More
Posted in Community Blog on

2017 CAAT Academy Program is available

Francois Busquet, CAAT Academy The CAAT Academy training program for 2017 has been published. The following sessions will be offered: Organs-on-a-chip @MIMETAS, Leiden (NL) In vitro skin & eye models – Part 1 @VUB, Brussels (BE) Liver models and AOP @Biopredic International, Rennes (FR) EDC in vitro models @Biodetection Systems, Amsterdam (NL) ADME @KUL, Leuven […]
0Read More
Posted in Community Blog on

Advancing non-animal testing methods: first set of novel knowledge tools published

Catherine Willett, HSUS From the European Commission: The Organisation for Economic Co-operation and Development (OECD) has recently published the first five adverse outcome pathways (AOP), three of which have been developed by the JRC. The AOPs are novel knowledge management tools in toxicology and are useful for supporting risk assessment to human health. They are […]
0Read More
Posted in Community Blog on

Three Key Approaches to Increasing Research Antibody Validation Defined at GBSI Workshop

Sherry Ward, AltTox Event Was Most Representative Gathering of Scientific Experts Ever Convened on the Topic PACIFIC GROVE, Calif., September 28, 2016—Leading experts from the international biomedical research community announced today that they have the fundamentals of what will become the first detailed standardized guidelines for validating research antibodies. The outcomes of this week’s Antibody […]
0Read More
Posted in Community Blog on

Conference: New Frontiers in 3D Cell Culture-based Screening Technologies

Catherine Willet, HSUS Full-day event on 3D microtissue models for more relevant translational screening methods and safety testing October 13 Baltimore, MD, USA Advanced 3D tissue models are changing the shape of in vitro testing for drug discovery and development from flat, monolayer cell culture to more complex 3D systems providing greater physiological relevance. The […]
0Read More
Posted in Community Blog on

BRAIN Initiative Updates: NSF encourages researchers with expertise in data science; Initiative seeks to include more diverse fields of science

Sherry Ward, AltTox NSF Announces Data Resources for the BRAIN Initiative September 22, 2016 …NSF, a partner in the BRAIN Initiative® supporting fundamental research across a spectrum of disciplines within neuroscience, has released a Dear Colleague Letter (see below) encouraging researchers with expertise in data science to partner with BRAIN Initiative projects, including projects funded by the […]
0Read More
Posted in Community Blog on

NICEATM Director Participates in Congressional Briefing

Catherine Sprankle, NICEATM NICEATM Director Warren Casey was a panelist for a September 13 Congressional briefing on “Alternatives to Animal Testing: Emerging Uses and Policy Implications.” Casey and other panelists discussed how to use non-animal and alternative toxicology and safety testing methods to better protect consumers and public health while using fewer animals. Topics considered […]
0Read More
Posted in Community Blog on

Computational Biology Symposium at NIH September 16

Catherine Sprankle, NICEATM PLoS Computational Biology is presenting a Computational Biology Symposium on the National Institutes of Health campus on Friday, September 16, from 9:30 a.m.-4:00 p.m. Keynote speakers will include Dr. David J. Lipman of the National Center for Biotechnology Information, Dr. Jennifer Lippincott-Schwartz of the Eunice Kennedy Shriver National Institute of Child Health […]
0Read More
Posted in Community Blog on

FDA Seeks Comment on Draft Guidance for Toxicokinetics Studies

Catherine Sprankle, NICEATM A U.S. Food and Drug Administration (FDA) notice in the September 8 Federal Register requested comments on draft guidance titled “ICH S3A Guidance: Note for Guidance on Toxicokinetics: The Assessment of Systemic Exposure in Toxicity Studies—Questions and Answers.” The draft guidance facilitates interpretation of the ‘‘S3A Guidance: The Assessment of Systemic Exposure […]
0Read More
Posted in Community Blog on

NICEATM Workshop Report Recognized as an NIEHS Paper of the Month

Catherine Sprankle, NICEATM The September issue of the Environmental Factor, the newsletter of the National Institute of Environmental Health Sciences (NIEHS), recognized the report on the Collaborative Workshop on Aquatic Models and 21st Century Toxicology as an NIEHS Intramural Paper of the Month. The workshop, organized by NICEATM and North Carolina State University, reviewed emerging […]
0Read More
Posted in Community Blog on

Announcement of 2016 ARDF Alternatives Research Grant awards

Sue A. Leary, ARDF The Alternatives Research & Development Foundation (ARDF) is pleased to announce the recipients of the 2016 Alternatives Research Grants. Luca Cucullo, PhD Texas Tech University Health Sciences Center, Amarillo, TX A humanized blood-brain tumor barrier model to assess drug delivery of chemotherapeutic treatment Dongeun (Dan) Huh, PhD University of Pennsylvania, Philadelphia, […]
0Read More
Posted in Community Blog on

Employment Opportunity: Corporate Liaison for PETA’s Regulatory Testing Department

Katherine Groff, PETA International Science Consortium Ltd. PETA’s Regulatory Testing Department is seeking a Corporate Liaison to join its growing team. This person will work with major corporations to replace and reduce animal testing. A successful candidate will attend corporate meetings and scientific conferences and maintain expertise in nonanimal test methods and international regulatory requirements. […]
0Read More
Posted in Community Blog on

CAAT Academy: Kidney toxicity testing and best practices

Francois Busquet, CAAT Dates: September 22-23, 2016 Location: Vienna, Austria, Evercyte Laboratories This 2-days training will give a comprehensive overview of the most relevant and robust 2D and 3D kidney cell culture models and in vitro applications for the assessment of kidney-associated cytotoxicity. Webinar will be available during the training but for the presentations only. […]
0Read More
Posted in Community Blog on

Upcoming calls for proposals

Sherry Ward, AltTox Engineering Next-Generation Human Nervous System Microphysiological Systems (R21) (PAR-16-397) and (R01) (PAR-16-398) Application Receipt/Submission Date(s): Standard dates apply through January 8, 2020 This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) with improved fidelity to complex human brain, spinal, peripheral nervous system and/or […]
0Read More
Posted in Community Blog on

U.S. Strategy and Roadmap for Implementing 21st Century Toxicity Testing Approaches

Catherine Sprankle, NICEATM The focus of the September 27 meeting of the Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) will be topics related to the development of a U.S. strategy and roadmap for implementing 21st century toxicity testing approaches. Background material and specific questions to be discussed by SACATM are included in an “In […]
0Read More
Posted in Community Blog on

Funding Opportunity for Alternative Methods Development

Catherine Sprankle, NICEATM The National Toxicology Program Interagency Center for the Evaluation of Alternative Methods (NICEATM) encourages U.S. small businesses involved in alternative methods development to apply for Small Business Innovation Research (SBIR) Phase IIB Awards for Validation and Commercialization of Approaches to Reduce Animal Use in Toxicology Testing offered by the National Institute of […]
0Read More
Posted in Community Blog on

Chips in Space: Webinar September 6

Catherine Sprankle, NICEATM The National Center for Advancing Translational Sciences (NCATS) and the Center for the Advancement of Science in Space are promoting a new program for research on the International Space Station United States National Laboratory (ISS-NL): we’re sending tissue chips to space! This program will leverage recent advances in tissue engineering and microfabrication […]
0Read More
Posted in Community Blog on

OECD lists newly “endorsed” AOPS

Catherine Willet, HSUS OECD has created a new web page to list Adverse Outcome Pathways that have undergone scientific review by experts and have been agreed by the OECD National Coordinators to represent the current state of knowledge: Four of the first five AOPs to have undergone this review are now posted: Adverse Outcome Pathway […]
0Read More
Posted in Community Blog on

NIH request for comments on scope of animal-human chimera research – deadline extended to September 6

Sherry Ward, AltTox “The National Institutes of Health (NIH) is requesting public comment on a proposal to amend Section IV and Section V of the NIH Guidelines for Human Stem Cell Research, and on the proposed scope of certain human-animal chimera research that will be considered internally by an NIH steering committee to provide programmatic […]
0Read More
Posted in Community Blog on

CRACK IT Announces 4 New Challenges; Partners Sought for Other Projects

Sherry Ward, AltTox The 2016 CRACK IT Challenges competition consists of the following four Challenges: Maximise: “To develop reliable predictions which confidently classify mixtures of chemicals for acute oral toxicity, skin and eye irritation with a focus on relevance for human safety. These should fulfill acute GHS Classification and Labeling requirements for non-encapsulated agrochemical mixtures […]
0Read More
Posted in Community Blog on

ICCVAM 2014-2015 Biennial Progress Report Now Available

Catherine Sprankle, NICEATM The ICCVAM 2014-2015 Biennial Progress Report is now available on the National Toxicology Program website. This report, prepared in accordance with requirements of the ICCVAM Authorization Act of 2000 (42 U.S.C. 285l-3), describes ICCVAM and ICCVAM agency activities from January 2014 through December 2015. Key ICCVAM, ICCVAM agency, and NICEATM accomplishments summarized […]
0Read More
Posted in Community Blog on

Webinar Series on Inhalation Toxicity Concludes September 8

Catherine Sprankle, NICEATM NICEATM and the PETA International Science Consortium (PISC) are co-hosting a webinar series on Alternative Approaches for Acute Inhalation Toxicity to Address Global Regulatory and Non-regulatory Data Requirements. The last webinar in the series will be Thursday, September 8, from 11:00 a.m. to 12:30 p.m. EDT. Dan Huh, Ph.D., University of Pennsylvania, […]
1Read More
Posted in Community Blog on

Workshop Report on Carcinogenicity of Mixtures Now Available

Catherine Sprankle, NICEATM An August 2015 workshop sponsored by the National Institute of Environmental Health Sciences evaluated the scientific support for the Low-Dose Mixture Hypothesis of Carcinogenesis and developed a research agenda. A report from this workshop is now available on the Environmental Health Perspectives website. NICEATM Deputy Director Nicole Kleinstreuer, Ph.D., was a breakout […]
0Read More
Posted in Community Blog on

Unilever offering annual award to promote alternatives in China

Catherine Willet, HSUS Unilever has launched an award to promote development and application of alternatives in China. The award called “Chinese Society of Toxicology Toxicology Unilever Alternatives Awards” was set up by Chinese society of toxicology, funded by Unilever. Two types of awards were announced: “Chinese Society of Toxicology Toxicology alternatives Unilever Innovation Award” (3 winners) and the “Chinese Society of Toxicology […]
0Read More
Posted in Community Blog on

NICEATM Requests Information on Acute Toxicity Testing Technologies

Catherine Sprankle, NICEATM In a July 18 Federal Register notice, NICEATM requested data and information on approaches and technologies currently used to identify substances with the potential to cause acute systemic toxicity when swallowed, inhaled, or absorbed through the skin. Respondents should provide information on any activities relevant to the development or validation of alternatives […]
0Read More
Posted in Community Blog on

OECD publishes guidance document on waiving mammalian acute toxicity tests

Kate Willett, HSUS The OECD has published a Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests. From the introduction: The OECD Guidelines for the Testing of Chemicals are continually evolving to reflect changing assessment practices. Acute toxicity tests are an area of focus for developing alternative assays to address animal […]
0Read More
Posted in Community Blog on

Beagle Freedom Prize for Non-Animal Methods

Sherry Ward, AltTox Beagle Freedom Project will award $250,000 in grants to applicants whose goal is to replace the common use of dogs and other animals in research, testing, and/or education with a non-animal approach. A total of five possible awards of $50,000 are scheduled, or larger sized grants are available to fewer awardees depending […]
0Read More
page 2 of 7

The AltTox Forum is now the AltTox Community Blog. To search historical postings from the AltTox Forum, visit its original address. For instructions on posting or subscribing, click on the teal box at the top of this page.

The views expressed in the AltTox Community Blog are those of the individuals posting them and not necessarily those of their home institution.