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2016 International Foundation for Ethical Research (IFER) Graduate Fellowship Awards

The International Foundation for Ethical Research (IFER) Board of Directors announced funding for three new Graduate fellowships in October. The new research projects are: T.J. Puls (graduate student) and Dr. Sherry Voytik-Harbin (faculty advisor), Purdue University, Engineering novel 3D tumor-stroma to bridge the gap between preclinical model and human clinical outcomes Danh Truong (graduate student) […]
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Dermal Technology Laboratory received the prestigious Queens’ Award for Enterprise in 2016

“Dermal Technology Laboratory (DTL) has been awarded one of the most coveted accolades in UK business. In recognition of its international growth and success over the past five years. DTL, based at Keele University Science and Innovation Park has received a Queen’s Award for Enterprise.” “Dermal Technology Laboratory specialises in in vitro dermal absorption studies that […]
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NIH funding announcement: Microphysiological Systems for Disease Modeling and Efficacy Testing

Source: http://grants.nih.gov/grants/guide/rfa-files/RFA-TR-16-017.html Title: Microphysiological Systems (MPS) for Disease Modeling and Efficacy Testing (UG3/UH3)  Funding Opportunity Announcement: RFA-TR-16-017 Purpose The purpose of the Microphysiological Systems (MPS) for Disease Modeling and Efficacy Testing Program is to develop highly reproducible and translatable in vitro models for preclinical efficacy studies through discovery and validation of translatable biomarkers, development of […]
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IIVS Releases Training Video to Replace Animals in Phototoxicity Testing

IIVS Releases Training Video to Replace Animals in Testing For Immediate Release Media Contact: Laura Henning 240-454-8459 lhenning@iivs.org GAITHERSBURG, MD – October 12, 2016 – Funded by a grant from the European Partnership for Alternative Approaches to Animal Testing (EPAA), the Institute for In Vitro Sciences, Inc.(IIVS) has released a technical training video that describes […]
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Many in vitro and in silico approaches encouraged in new funding opportunity from the Bill & Melinda Gates Foundation – Proposals due November 9

Grant Opportunity title: Develop Novel Platforms to Accelerate Contraceptive Drug Discovery (Round 18) Source: http://gcgh.grandchallenges.org/challenge/develop-novel-platforms-accelerate-contraceptive-drug-discovery-round-18 Deadline: 9 Nov 2016 – 11:30am PST The Challenge While access to a range of appropriate and desirable contraceptive methods can have a broad beneficial impact on the lives of women, men and their families, this goal is currently not […]
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Three Key Approaches to Increasing Research Antibody Validation Defined at GBSI Workshop

Sherry Ward, AltTox Event Was Most Representative Gathering of Scientific Experts Ever Convened on the Topic PACIFIC GROVE, Calif., September 28, 2016—Leading experts from the international biomedical research community announced today that they have the fundamentals of what will become the first detailed standardized guidelines for validating research antibodies. The outcomes of this week’s Antibody […]
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BRAIN Initiative Updates: NSF encourages researchers with expertise in data science; Initiative seeks to include more diverse fields of science

Sherry Ward, AltTox NSF Announces Data Resources for the BRAIN Initiative September 22, 2016 …NSF, a partner in the BRAIN Initiative® supporting fundamental research across a spectrum of disciplines within neuroscience, has released a Dear Colleague Letter (see below) encouraging researchers with expertise in data science to partner with BRAIN Initiative projects, including projects funded by the […]
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Announcement of 2016 ARDF Alternatives Research Grant awards

Sue A. Leary, ARDF The Alternatives Research & Development Foundation (ARDF) is pleased to announce the recipients of the 2016 Alternatives Research Grants. Luca Cucullo, PhD Texas Tech University Health Sciences Center, Amarillo, TX A humanized blood-brain tumor barrier model to assess drug delivery of chemotherapeutic treatment Dongeun (Dan) Huh, PhD University of Pennsylvania, Philadelphia, […]
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Upcoming calls for proposals

Sherry Ward, AltTox Engineering Next-Generation Human Nervous System Microphysiological Systems (R21) (PAR-16-397) and (R01) (PAR-16-398) Application Receipt/Submission Date(s): Standard dates apply through January 8, 2020 This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) with improved fidelity to complex human brain, spinal, peripheral nervous system and/or […]
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NIH request for comments on scope of animal-human chimera research – deadline extended to September 6

Sherry Ward, AltTox “The National Institutes of Health (NIH) is requesting public comment on a proposal to amend Section IV and Section V of the NIH Guidelines for Human Stem Cell Research, and on the proposed scope of certain human-animal chimera research that will be considered internally by an NIH steering committee to provide programmatic […]
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CRACK IT Announces 4 New Challenges; Partners Sought for Other Projects

Sherry Ward, AltTox The 2016 CRACK IT Challenges competition consists of the following four Challenges: Maximise: “To develop reliable predictions which confidently classify mixtures of chemicals for acute oral toxicity, skin and eye irritation with a focus on relevance for human safety. These should fulfill acute GHS Classification and Labeling requirements for non-encapsulated agrochemical mixtures […]
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Beagle Freedom Prize for Non-Animal Methods

Sherry Ward, AltTox Beagle Freedom Project will award $250,000 in grants to applicants whose goal is to replace the common use of dogs and other animals in research, testing, and/or education with a non-animal approach. A total of five possible awards of $50,000 are scheduled, or larger sized grants are available to fewer awardees depending […]
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REACH annexes amended on use alternative methods

Sherry Ward, AltTox The European Chemicals Agency (ECHA) provides the latest news on chemical registration obligations under REACH on their REACH 2018 web page. “The REACH requirements for skin corrosion/irritation, serious eye damage/eye irritation, acute dermal toxicity and skin sensitisation are changing, making non-animal testing the default requirement.” The changes and new requirements are explained […]
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European Pharmacopoeia Commission adopts revised general chapter on monocyte activation test to facilitate reduction in animal testing

Sherry Ward, AltTox Source: https://www.edqm.eu/en/node/15240 “During its 155th Session, held in Strasbourg on 21-22 June 2016, the European Pharmacopoeia Commission adopted a revision of the general chapter Monocyte-activation test (2.6.30) in order to make it more widely useable by stakeholders and thus facilitate a reduction in testing on live animals.” The press release provides additional […]
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FDA requests additional information to address data gaps for consumer hand sanitizers

Sherry Ward, AltTox The US Food and Drug Administration issued a proposed rule requesting additional scientific data to support the safety and effectiveness of certain active ingredients used in consumer antiseptic rubs (hand sanitizers) marketed over-the-counter (OTC). The FDA’s request for more data is intended to help the agency ensure that regular use of these […]
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NIH Releases a Request for Information Seeking Guidance for Opportunities in Neuroethics; Responses Due July 29, 2016

Sherry Ward, AltTox Source: https://brainupdate.nih.gov/2016/06/07/nih-releases-a-request-for-information-seeking-guidance-for-opportunities-in-neuroethics June 7, 2016 NIH solicits input to identify a set of core ethical issues associated with research involving the human brain and resulting from advancements in neurotechnology research and development…. The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative® is aimed at revolutionizing our understanding of the human brain. By […]
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View presentations from NTP’s Botanical Dietary Supplement Safety Workshop

Sherry Ward, AltTox Videocasts now available for the April 26-27, 2016 NTP workshop, “Addressing challenges in the assessment of botanical dietary supplement safety.” Overall, it was a well-organized and informative meeting with excellent presentations. The many challenges in assessing the safety of botanical products coupled with an emerging demand for their safety assessment suggests this […]
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Evidence-based Toxicology Collaboration news

Sherry Ward, AltTox The Evidence-based Toxicology Collaboration (EBTC) at Johns Hopkins Bloomberg School of Public Health is a collaboration of stakeholders “united in their vision to improve the public health outcomes and reduce human impact on the environment by bringing evidence-based approaches to safety sciences.” EBTC news this week includes their launch of an attractive, […]
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EUSAAT & Linz 2016: Abstracts and Young Scientist Travel Awards applications – Deadlines Extended to June 15

Sherry Ward, AltTox EUSAAT Young Scientist Travel Awards (YSTA) To get elected for the EUSAAT 2016 YSTA program, young scientists up to 35 years, e.g. graduate, postgraduate, or PhD students, must submit three documents until 15th June 2016: an abstract via our online submission form an application form for the EUSAAT 2016 YSTA program, and provide a […]
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NIH Common Fund Request for Information by June 22 on “Characterizing and Understanding the Organization of Individual Cells within Human Tissues”

Sherry Ward, AltTox Source: http://grants.nih.gov/grants/guide/notice-files/NOT-RM-16-025.html Notice Number: NOT-RM-16-025 Key Dates         Release Date: May 26, 2016         Response Date: June 22, 2016 Issued by Office of Strategic Coordination (Common Fund) Purpose This is a Request for Information (RFI) to solicit input regarding a proposal for a new Common Fund program aimed at characterizing and understanding organization […]
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Horizon 2020 SME Innovation Associate: Connecting European small and medium-sized enterprises (SMEs) with researchers

Sherry Ward, AltTox The European Union recently launched a EUR 7 million pilot action aiming to support dynamic SMEs in recruiting researchers to explore innovative business ideas. Enterprises have until 30 June 2016 to submit a 10-page application explaining the business idea, the required skills and the envisaged role of the researcher within the company. […]
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NAVS Selects 2016 Humane Science Award Recipients at Intel ISEF

Contributor: Sherry Ward, AltTox Source: http://act.navs.org/site/MessageViewer?em_id=1384.0&dlv_id=5282 Last week, NAVS honored promising young scientists at the Intel International Science and Engineering Fair (Intel ISEF) —the world’s largest international science competition for high school students—in Phoenix, Arizona. This is the 15th year that we have participated in this preeminent science fair—presenting our annual Humane Science Award, which […]
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US-Canada Regulatory Cooperation Council Meeting: May 4-5, Washington, DC

Contributor: Sherry Ward, AltTox Source: USDA Animal and Plant Health Inspection Service Weekly Digest Bulletin, 04/19/2016 Dear RCC stakeholders: We invite you to participate in the U.S.–Canada Regulatory Cooperation Council Stakeholder Meeting, to be held at the Embassy of Canada in Washington, D.C. on May 4-5 2016. Please indicate your attendance at this two-day event […]
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New environmental policy reports from Science for Environment Policy

Contributor: Sherry Ward, AltTox Science for Environment Policy, a free news and information service published by Directorate-General Environment, European Commission, has published two new reports as part of their work to support policymakers with “quality environmental research for evidence-based policy.” Identifying emerging risks for environmental policies. Future Brief 13: “While identifying, predicting and monitoring known […]
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NIH funding: Cell line identification tools; Human tissue models for infectious disease

Contributor: Sherry Ward, AltTox Tools for Cell Line Identification (SBIR [R43/R44]); PA-16-186 Due Dates: Standard dates through April 6, 2019 Funding Opportunity Purpose: This Funding Opportunity Announcement (FOA) is intended to address the problem of misidentified cell lines. Many advances in biomedical science have arisen from studies of cultured cell lines, which are widely used […]
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EDQM symposium, “The Challenges of Quality Requirements for Fish Vaccines,” call for posters by April 15

Contributor: Sherry Ward, AltTox Source: European Pharmacopoeia Work Programme Symposium 10 May 2016 to 11 May 2016; Oslo, Norway Programme Overview Global production of fish from aquaculture has grown substantially in the past decade and this growth has brought with it many economic benefits and challenges. Like other forms of animal production, disease prevention and […]
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Vaccines for Veterinary Use: A step further on the 3Rs path

Contributor: Sherry Ward, AltTox Source: European Pharmacopoeia News 10 March 2016 As part of the Ph. Eur. Commission’s efforts to replace in vivo with in vitro methods, around 40 inactivated vaccine-specific monographs and the general monograph Vaccines for veterinary use (0062) were adopted at its 153rd Session in November 2015. These texts will be published […]
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Mechanistic Oral Absorption Modeling and Simulation – FDA Workshop, May 19, 2016

Contributor: Sherry Ward, AltTox Source: Federal Register FDA public workshop: Mechanistic Oral Absorption Modeling and Simulation for Formulation Development and Bioequivalence Evaluation Date: May 19, 2016, from 8:30 a.m. to 4:30 p.m.; must register on or before April 19, 2016 Location: FDA Conference Center at the White Oak Campus, Maryland Purpose of the workshop Share […]
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New Guidance Documents for Pesticide Testing and GHS Pilot Program Support EPA OPP’s Goal to Reduce Animal Testing

Contributor: Sherry Ward, AltTox Sources: EPA Pesticide Program Updates (e-newsletter), March 17, 2016; and Letter to Stakeholders… Yesterday, in this open letter to stakeholders, EPA’s Office of Pesticide Programs (OPP) announced progress on “its goal to significantly reduce the use of animals in acute effects testing”: Letter to Stakeholders on EPA Office of Pesticide Programs’s Goal to Reduce Animal Testing […]
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February ECHA Newsletter

Contributor: Sherry Ward, AltTox The February issue of the ECHA Newsletter has many informative articles, including this one explaining the ways ECHA promotes the use of alternative methods: Alternatives to animal testing – what’s new in 2016? “This year, the focus is on promoting alternative methods and approaches that are relevant for the information requirements […]
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Congratulations to the 2015 NC3Rs Prize Winners

Contributor: Sherry Ward, AltTox Source: https://www.nc3rs.org.uk/news/dogs-3d-tissue-models-2015-3rs-prize “Three pieces of outstanding published research with 3Rs impacts have been given awards in this year’s 3Rs Prize competition, run by the NC3Rs, and sponsored by GlaxoSmithKline…. Two papers were declared joint winners of the 2015 Prize. The first describes a 3D model of the embryonic human brain created […]
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2016 ALTERNATIVES RESEARCH GRANT PROGRAM

Contributor: Sherry Ward, AltTox Source: Alternatives Research & Development Foundation The Alternatives Research & Development Foundation, a U.S. leader in the funding and promotion of alternatives to the use of laboratory animals in research, testing, and education, is currently soliciting research proposals for its 2016 Alternatives Research Grant Program. For over 20 years, this innovative […]
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EU public survey open until March 11: “Accelerating progress in the Replacement, Reduction and Refinement of animal testing through better knowledge sharing”

Contributor: Sherry Ward, AltTox Source: https://eurl-ecvam.jrc.ec.europa.eu/alternatives-to-animal-testing-eu-public-survey-launched Following the European Commission’s Communication published in response to the European Citizens’ Initiative “Stop Vivisection”, the JRC’s Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is conducting a public survey to solicit input from individuals and organisations to identify all types of knowledge sources that might be relevant […]
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Annual BioPolicy Summit on Research Reproducibility in Washington, DC, February 9th

Contributor: Sherry Ward, AltTox Source: GBSI Media Alert New Reproducibility2020 initiative will provide framework for action On Tuesday, February 9, at 12:00 noon EST, Global Biological Standards Institute (GBSI) will host its 2016 BioPolicy Summit at the Newseum in Washington, DC. The Summit welcomes premiere life science thought leaders as speakers, panelists, and guests who will focus on […]
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AVON Breast Cancer Research Program

Contributor: Sherry Ward, AltTox Letters of Intent for research funding through the AVON Breast Cancer Research Program are due January 7, 2016 for proposals to be submitted later in 2016 (by invitation only). Research priorities Research questions [they] hope to answer to further the development of breast cancer prevention strategies include, but are not limited […]
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NCATS News

Contributor: Sherry Ward, AltTox The National Center for Advancing Translational Sciences (NCATS) is one of 27 Institutes and Centers at the National Institutes of Health (NIH). It was established in 2012 “to transform the translational science process so that new treatments and cures for disease can be delivered to patients faster” (http://www.ncats.nih.gov/about/center). One of the […]
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2016 Funding Opportunities

Contributor: Sherry Ward, AltTox (1) Exploratory/Developmental Bioengineering Research Grants (EBRG): http://grants.nih.gov/grants/guide/pa-files/PA-16-040.html Application due dates: March 16, July 16, and November 16, 2016 These awards are open to various types of organizations, including small business. The R21 mechanism supports short-term exploratory research projects. “The purpose of this FOA is to  encourage submission of EBRG applications which […]
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CVB Notice 15-13: Alternative approach to hamster potency test for several Leptospira serogroups could reduce animal use by 50%

Contributor: Sherry Ward, AltTox The Center for Veterinary Biologics (CVB) recently added CVB Notice 15-13, Option to Remove Back-titration Hamsters from In Vivo Potency Tests for Leptospira Serogroups Canicola and Icterohaemorrhagiae, to its website: https://www.aphis.usda.gov/animal_health/vet_biologics/publications/notice_15_13.pdf The purpose of this notice is to inform interested parties that the CVB will allow an exemption from the titration […]
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Results from the 2015 GBSI survey on cell line authentication practices

Contributor: Sherry Ward, AltTox AltTox’s May 2015 “In the Spotlight,” Are we inseparable? Reproducible bioassays and authenticated cell lines (http://alttox.org/are-we-inseparable-reproducible-bioassays-and-authenticated-cell-lines-new-initiatives-by-the-global-biological-standards-institute/), asked readers to participate in a survey on cell line authentication practices being conducted by the Global Biological Standards Institute (GBSI). The results are now available! GBSI’s Cell Authentication Survey Shows Little Progress in a […]
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ECHA asks registrants about their consideration of alternative methods

Contributor: Sherry Ward, AltTox Editor’s Note: The AltTox Resource Center page, Searching for Non-animal Toxicity Test Methods, provides links to many sources of information on non-animal test methods: http://alttox.org/resource-center/searching-for-non-animal-toxicity-testing-methods/ ______________________________________ ECHA asks registrants to show how they considered alternative methods before consulting on testing proposals Source: http://echa.europa.eu/view-article/-/journal_content/title/echa-asks-registrants-to-show-how-they-considered-alternative-methods-before-consulting-on-testing-proposals To further ensure that testing on animals is […]
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October 30 Public Meeting on the Coordinated Framework on Biotechnology

Contributor: Sherry Ward, AltTox The Environmental Protection Agency (EPA), Food and Drug Administration (FDA) and United States Department of Agriculture (USDA) will hold a public meeting on October 30, 2015, to discuss the memorandum entitled, “Modernizing the Regulatory System for Biotechnology Products,” issued by the Executive Office of the President on July 2, 2015. The […]
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