The EHS Hazard Assessment programme is actively working to increase the regulatory acceptance of QSARs methods, tools and approaches such as the QSAR Toolbox and to make these technologies more accessible and transparent. The QSAR toolbox is a software application intended to the use of governments, chemical industry and other stakeholders in filling gaps in […]
The International Foundation for Ethical Research (IFER) is now accepting pre-proposal applications for 2018-2019 Graduate Fellowships. Applications are due no later than 11:59 PM CST on Monday, April 30, 2018. IFER Graduate Fellowships are one-year grants of up to $12,500 for projects that support the development, acceptance and implementation of innovative scientific methodologies that advance […]
Integrating large quantities of data from multiple, disparate sources can create new opportunities to understand complex environmental health questions. However, combining new types and larger quantities of data to inform a specific decision presents many new challenges. For example, investigators must develop methods to reliably integrate data from designed experiments with data re-purposed from other uses, […]
The Society of Environmental Toxicology and Chemistry will hold a meeting on High Throughput Screening and Environmental Risk Assessment, State of the Science and Emerging Applications on April 16-18 at the Durham Convention Center in Durham, North Carolina. This meeting will provide environmental toxicologists and risk assessors with an introduction to high throughput data and […]
The ECHA Board of Appeal has annulled a decision by ECHA requiring an ingredients supplier to test a personal care ingredient on animals in Europe. Read more: https://www.cosmeticsdesign-europe.com/Article/2018/01/03/ECHA-clarifies-animal-testing-position-for-cosmetics-ingredient-a-significant-step-for-alternatives
GAITHERSBURG, MD – Jan. 8, 2018 – The Institute for In Vitro Sciences, Inc. (IIVS) today announced a collaboration with BASF to import a non-animal, cell based, safety test into China. The LuSens test, developed by BASF, is an in vitro test to detect the sensitization potential of chemicals to human skin. The test was […]
Recent scientific advances have made genome editing technologies—a suite of biological tools for making precise additions, deletions, and alterations to the DNA and RNA of living cells– more rapid, efficient, and flexible than ever before. Join experts in molecular biology, toxicology, and public health to explore opportunities for using genome (and epigenome) editing technologies in […]
The Center for the Advancement of Science in Space (CASIS) has partnered with the National Institutes of Health (NIH) and the National Science Foundation (NSF) to fund new opportunities for conducting research onboard the International Space Station. The NIH-CASIS Coordinated Microphysiological Systems Program for Translational Research in Space promotes the development of tissue chips to […]
The National Institute of Environmental Health Sciences (NIEHS) is offering Small Business Innovation Research (SBIR) grants to develop novel in vitro systems using cells from experimental animal models typically used for toxicology testing. The intent is that these systems will replicate biological responses within the corresponding animal tissues or organs. When developed and validated, these […]
The journal Applied In Vitro Toxicology is accepting manuscript submissions for a special issue on alternative approaches for inhalation toxicity testing. Submissions must be received by December 15. Inhalation toxicity testing provides information for hazard labeling and risk management of chemicals when there is potential for exposure of the respiratory tract. Regulatory test guidelines typically […]
In an article published December 6 on the FDA Voice blog, the U.S. Food and Drug Administration (FDA) announced publication of FDA’s Predictive Toxicology Roadmap for integrating predictive toxicology methods into safety and risk assessments. The Predictive Toxicology Roadmap presents a framework for new or enhanced FDA engagement in the science of toxicology that includes […]
Each year the NC3Rs awards a prize to recognize an outstanding original contribution to scientific and technological advances in the 3Rs, published in the last three years. The award consists of a £28k prize grant and £2k personal award. The competition has a deadline of 4 pm (GMT) on Monday 4 December 2017. For further […]
Discuss the key factors that influence how new science is incorporated into the environmental health decision making process at a free National Academies of Sciences, Engineering, and Medicine workshop on November 20-21 in Washington, DC and via webcast. New approaches for understanding the toxicity of chemicals in humans—from high-throughput cell-based in vitro studies to tissue […]
A recording of the plenary session held during the November 2, 2017 “Alternative Test Methods to Reduce Vertebrate Animal Testing under the Toxic Substances Control Act” meeting is now available on the National Institutes of Health website at https://videocast.nih.gov/summary.asp?Live=26469&bhcp=1
Planning to be in Minneapolis next week for the Society of Environmental Toxicology and Chemistry (SETAC) North America Annual Meeting? Please join us for “Improving Species Extrapolation for Protecting Endangered Species: What Is Available and What Is Needed?” Currently, data used to protect endangered species has the unintended consequence of helping to increase animal testing […]
The Integrated Case Studies Project was launched in 2015 to increase experience with the use of Integrated Approaches For Testing And Assessment (IATA) by developing case studies, which constitute examples of predictions that are fit for regulatory use. The aim is to create common understanding of using novel methodologies and the generation of considerations/guidance stemming […]
The Physicians Committee for Responsible Medicine is seeking a Research and Testing Coordinator to contribute to our efforts to replace animals in basic and medical research with human-relevant research methods by implementing education and outreach programs and conducting research. If you are a professional with a degree in the life sciences, apply today! https://www.pcrm.org/about/careers/research-and-testing-coordinator
Sue Leary, ARDF The Alternatives Research & Development Foundation (ARDF), which funds and promotes alternatives to the use of laboratory animals in research, testing, and education, is currently soliciting research proposals. • Maximum award per project: $40,000 • Deadline: May 1, 2017 (for electronic submission, request Dropbox by April 27, 2017) • Notification of recipients: […]
Solmaz Barazesh Spence, The National Academies of Sciences, Engineering, and Medicine Discuss the current thinking surrounding causal models, how novel approaches and tools are relevant for environmental health, and how they can be incorporated into the decision making process at a free National Academies of Sciences, Engineering, and Medicine workshop on March 6-7 in Washington, […]
Helen Gill, Cyprotex Discovery Ltd Cyprotex’s Chemical and Cosmetics Testing Guide is a valuable resource for anyone involved in safety testing of industrial chemicals, pesticides, cosmetics and personal care products. It covers current legislation, skin and ocular testing approaches, mutagenicity/genotoxicity testing and endocrine disruption testing, and focuses predominantly on non-animal testing methods. Order your free […]
Mardas Daneshian, CAAT-Europe at the University of Konstanz Information Day on “Progress in Alternative Methods in Toxicology and Biomedicine” July 8th 2016 09:00 – 16:00 Konzil Konstanz, Konstanz, Germany Toxicology traditionally relies on the use of animals to derive information relevant for human wellbeing and safety. Today, human cell-based alternative methods to animal use have […]
Ashley Felder, PCRM The Physicians Committee for Responsible Medicine is currently looking for a Toxicologist to join our growing Research Policy Team. We’re looking for someone that will spearhead our efforts to implement human-relevant test methods and minimize the use of animals in domestic and international chemical testing policies and guidelines. The candidate will work […]
Contributor: Myra Westmoreland, NIEHS National Institute of Environmental Health Sciences (NIEHS) is seeking a dynamic, highly motivated Senior Scientist to serve as NICEATM Director. NICEATM is the primary federal resource for the development, validation, and evaluation of new toxicological testing methods that reduce, refine, or replace the use of animals (“alternative methods”). NICEATM provides scientific […]
Contributor: Bonnie Earnhardt, NIH/NIEHS NIEHS is seeking a dynamic, highly motivated Senior Scientist to serve as NICEATM Director. NICEATM is the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, an office within the Division of the National Toxicology Program. NICEATM is the primary federal resource for the development, validation, and evaluation of new […]
Contributor: Stéphanie Rémola, HeMiBio Management Team In January 2011 the European Commission and Cosmetics Europe jointly launched a European research initiative aiming at a common strategy towards the replacement of current repeated dose systemic toxicity testing in human safety assessment. The aim of HeMiBio as part of this initiative was to generate a liver-simulating device […]
Contributor: Solmaz Spence, National Academies of Sciences, Engineering, and Medicine Metabolomics—the study of the chemical fingerprints that cellular processes leave behind—is emerging as an important way to characterize exposure. On May 28-29, join the committee on Emerging Science for Environmental Health Decisions and researchers, professionals, and policy experts for a free workshop that will explore […]
Author: Sue A. Leary, Alternatives Research & Development Foundation (ARDF) The deadline is fast approaching for applications to the Alternatives Research Grant Program of ARDF. Grants of up to $40,000 are available to support individual projects of scientific merit and feasibility with potential to significantly reduce or replace laboratory animal use. Preference will be given […]
Author: Joseph Manuppello, PETA Public Release: 1-Apr-2015 The tobacco industry and regulatory authorities should support more relevant and less costly in vitro toxicology testing methods over unreliable animal testing, according to a review of research advances published this week in the comment pages of the peer-reviewed scientific journal Alternatives to Laboratory Animals The article by […]
Author: Nate Leskovic, New England Anti-Vivisection Society The New England Anti-Vivisection Society (NEAVS), a national nonprofit located in Boston dedicated to promoting alternatives to research and testing on animals, is currently accepting applications for a $40,000 postdoctoral fellowship grant for a woman interested in and committed to developing, validating, or using non-animal alternatives in the […]
Author: Sherry Ward, AltTox Systems Developmental Biology for Understanding Embryonic Development and the Ontogeny of Structural Birth Defects (R01) (PAR-15-020): http://grants.nih.gov/grants/guide/pa-files/PAR-15-020.html Application Due Dates: Earliest Submission Date: December 15, 2014 Letter of Intent Due Date: 30 days before the application due date Application Due Date(s): January 15, 2015, November 10, 2015, November 10, 2016, by […]
Author: Catherine Willett, HSUS The National Center for Computational Toxicology is seeking a Senior Leader (SL) to serve as the Deputy Director. This position is currently open until November 25, 2014, to any U.S. citizen, and is located in the Durham, NC area. Please distribute to qualified candidates whom you believe may be interested. Please […]
Author: Rebecca Ram, Lush Cosmetics Lush Prize 2014- Is One R the new Three Rs? …a one day conference on Friday 14th November 2014 at RIBA in London W1B 1AD The impact of 21st century toxicology ideas on replacing animal testing Does the consensus building around 21st Century Toxicology – a wholly replacement model […]
Author: Marilyn Matevia, HSUS The OECD Advisory Group on Endocrine Disrupters Testing and Assessment has put out a communique urging OECD countries to “support for the development of non-animal tests for the thyroid pathway that are applicable to the screening and assessment of endocrine disruption in humans and wildlife.” More information here: http://www.oecd.org/chemicalsafety/oecd-encourages-development-of-non-animal-test-methods-for-detection-of-thyroid-disrupters.htm
Author: Sherry Ward, AltTox The response date for the Request for Information “Consideration of Sex As a Biological Variable in Biomedical Research” (NOT-OD-14-128) (http://grants.nih.gov/grants/guide/notice-files/NOT-OD-14-128.html) has been extended from October 13, 2014, to October 24, 2014 (http://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-012.html). “This Request for Information seeks input from the research community and other interested stakeholders on the following topics regarding […]
Author: Sherry Ward, AltTox EPA updates ChemView and requests user feedback EPA News Release: http://yosemite.epa.gov/opa/admpress.nsf/bd4379a92ceceeac8525735900400c27/8eae38498d0421bd85257d6a00614e8b%21OpenDocument Release Date: 10/07/2014 “WASHINGTON – The U.S. Environmental Protection Agency (EPA) has posted additional data and added new functions to ChemView, EPA’s publicly-accessible, one-stop online tool to find information for chemicals regulated under the Toxic Substances Control Act (TSCA). […]
Author: Marilyn Matevia, HSUS Read about the 2014 International Foundation for Ethical Research graduate fellowship winners in the new “In the Spotlight” article on AltTox: http://alttox.org/ifer-funds-new-graduate-fellowships-research-development-alternatives-use-animals-science/ Also, the October AltTox Digest is out and available here: http://eepurl.com/54Mr9 If you’d like to subscribe to the AltTox Digest, you can sign up here: http://alttox.org/alttox-digest/ If you are […]
Author: Catherine Willett, HSUS Fall 2014 Symposium Low Dose Effects / Non-Monotonic Responses of Endocrine Disruptors October 24, 2014 Searle Center Lecture Hall, Duke University RSVP HERE Agenda ITEHP Fall 2014 Symposium (view agenda)http://sites.nicholas.duke.edu/envhealth/events/fall-2014-itehp-symposium-low-dose-effects-non-monotonic-responses-of-endocrine-disruptors/ ABSTRACT: The publication of “Our Stolen Future” helped to spur research on endocrine disrupting contaminants (EDCs) and investigating their potential affects […]
Author: Daniela Parodi, University of California – Los Angeles Dear Colleague, We would like to invite you to participate in an international survey that examines the use of alternative approaches for toxicity testing in various settings. In particular, we are interested in information regarding your views on alternative approaches and about the various factors […]
Author: Marilyn Matevia, HSUS From the press release: “… the U.S Environmental Protection Agency and the European Commission Joint Research Centre has today launched the Adverse Outcome Pathway Knowledge Base (AOP KB). This is a web-based platform which aims to bring together all knowledge on how chemicals can induce adverse effects, therefore providing a […]
Author: Sherry Ward, AltTox The Japanese Center for the Validation of Alternative Methods (JaCVAM) has for many years provided a table on their website that shows the validation status of alternative test methods accepted by or under some level of consideration in Japan. See this page: http://www.jacvam.jp/en_effort/ JaCVAM Statements and other validation study documents […]
Author: Marilyn Matevia, HSUS “InnoSysTox is a joint call by ZonMw and the German Federal Ministry of Education and Research (BMBF). Within ZonMw this joint call is part of the More Knowledge with Fewer Animals programme. … Aim of the joint call: Development of innovative systems-biology-based 3R methods in toxicology and/or Application of new and […]
Author: Sherry Ward, AltTox The Japanese Society for Alternatives to Animal Experiments (JSAAE) is accepting proposals for the 8th “Mandom International Research Grants on Alternative to Animal Experiments.” Application deadline: January 31, 2015. Eligible applicants: Researchers around the world, mainly focusing on Asia, who are members of the JSAAE and engaged in research in […]
Author: Jessica Sandler, People for the Ethical Treatment of Animals http://www.eurekalert.org/pub_releases/2014-09/pfte-psc091214.php PETA Science Consortium experts to present at international nanotechnology workshop PETA International Science Consortium, Ltd., is a sponsor of Nano Risk Analysis II Washington, D.C. – Experts from the PETA International Science Consortium will present strategies for optimizing nonanimal testing methods at a […]
Author: Sherry Ward, AltTox Call for tender – “Integrating toxicokinetics in chemical risk assessment: application to human, animal and environmental risk assessment (OC/EFSA/SCER/2014/06)” Deadline: 20 October 2014 Overall objective: “The overall objective of the contract resulting from the present procurement procedure is to develop tools and models to integrate TK data and predict TK […]
Author: Sherry Ward, AltTox “The U.S. Food and Drug Administration has completed a review of how the agency evaluates the harmful effects of chemicals in foods, cosmetics, dietary supplements, animal food/feed, and veterinary drugs. Based on the findings, the agency is taking steps to strengthen internal processes. The chemical safety assessment review is the […]
Author: Sherry Ward, AltTox (1) Use of Induced Pluripotent Stem Cells as Screening Tools and Therapeutics September 11, 2014, 2 pm Eastern Time The focus of this webinar is on the use of Induced Pluriopotent Stem Cells (iPSCs)– used as a tool for disease modeling, target identification, or toxicity assessment, or as a cell […]
Author: Marilyn Matevia, HSUS EPA Press release, Sept. 9 (available here: http://yosemite.epa.gov/opa/admpress.nsf/0/BD92838AD510DAD885257BE1005AB889) “The U.S. Environmental Protection Agency (EPA) has launched a web-based tool, called ChemView, to significantly improve access to chemical specific regulatory information developed by EPA and data submitted under the Toxic Substances Control Act (TSCA). ‘This online tool will improve access to […]
