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Author Archive for: "AltTox"
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Hands-On Seminar: Creating an Adverse Outcome Pathway in the AOP Wiki

If you are attending the Society of Toxicology’s annual meeting in Baltimore next month, the Human Toxicology Project Consortium (HTPC) and the Physicians Committee for Responsible Medicine (PCRM) invite you to deepen your understanding of the AOP Wiki and gain experience entering an Adverse Outcome Pathway in a structured, hands-on seminar Tuesday evening, March 14. […]
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SOT Satellite Meeting: Updates on Activities Related to 21st Century Toxicology and Related Efforts

If you’re planning to attend the Society of Toxicology conference in Baltimore this March, please join the Center for Alternatives to Animal Testing (CAAT), the Human Toxicology Project Consortium (HTPC), and the Human Toxome Project Consortium for the annual satellite meeting on 21st century toxicology activities and related efforts, Thursday, March 16 from noon to […]
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AltTox at SOT 2017 in Baltimore, Maryland

As in previous years, AltTox Editorial Board and Management Team members will be at the annual meeting of the Society of Toxicology (Baltimore, Maryland) to share research with thousands of other toxicologists. AltTox Editorial Board and/or Management Team members are co-authors of the following posters (listed by abstract #/poster board #): 1209/333: Systematic Reviews as […]
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ECHA scientists publish analysis supporting new guidance to reduce acute oral toxicity tests

Sonja von Aulock, ALTEX Scientists from the European Chemicals Agency (ECHA) around Andrea Gissi and Kimmo Louekari have published an analysis of data in the REACH registration database that supports the use of sub-acute toxicity results, together with other relevant information, to cover the acute toxicity standard requirements for REACH registration in a weight of […]
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2017 CAAT Academy Program is available

Francois Busquet, CAAT Academy The CAAT Academy training program for 2017 has been published. The following sessions will be offered: Organs-on-a-chip @MIMETAS, Leiden (NL) In vitro skin & eye models – Part 1 @VUB, Brussels (BE) Liver models and AOP @Biopredic International, Rennes (FR) EDC in vitro models @Biodetection Systems, Amsterdam (NL) ADME @KUL, Leuven […]
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Employment Opportunity: Corporate Liaison for PETA’s Regulatory Testing Department

Katherine Groff, PETA International Science Consortium Ltd. PETA’s Regulatory Testing Department is seeking a Corporate Liaison to join its growing team. This person will work with major corporations to replace and reduce animal testing. A successful candidate will attend corporate meetings and scientific conferences and maintain expertise in nonanimal test methods and international regulatory requirements. […]
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CAAT Academy: Kidney toxicity testing and best practices

Francois Busquet, CAAT Dates: September 22-23, 2016 Location: Vienna, Austria, Evercyte Laboratories This 2-days training will give a comprehensive overview of the most relevant and robust 2D and 3D kidney cell culture models and in vitro applications for the assessment of kidney-associated cytotoxicity. Webinar will be available during the training but for the presentations only. […]
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OECD publishes guidance document on waiving mammalian acute toxicity tests

Kate Willett, HSUS The OECD has published a Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests. From the introduction: The OECD Guidelines for the Testing of Chemicals are continually evolving to reflect changing assessment practices. Acute toxicity tests are an area of focus for developing alternative assays to address animal […]
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2017 CAAT Grant Pre-proposals: Deadline extended to May 16

Contributor: Pascaline Clerc, HSUS Deadline for preproposals: May 16, 2016 The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) is soliciting projects that focus on the implementation of the NAS Report, Toxicity Testing in the 21st Century: A Vision and a Strategy in the following areas: Proposals Relating to Toxicology: Maximum grant amount is […]
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‘Nano’ Today

Introduction Nanotechnology encompasses a wide variety of nanosized materials, or nanomaterials (NMs), which are defined by the International Organization for Standardization (ISO) as materials with any external dimension in the nanoscale or having internal structure or surface structure in the nanoscale (ISO, 2011). There is a large number of NMs in the global marketplace with […]
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Join SETAC in Advancing the Adverse Outcome Pathway Concept

Contributor: Marilyn Matevia, HSUS An announcement from the Society of Environmental Toxicology and Chemistry (SETAC): “The Society for Environmental Toxicology and Chemistry (SETAC) is initiating a horizon scanning effort to advance the science and application of the Adverse Outcome Pathway (AOP) framework. This horizon scanning approach will allow us to identify and begin to address […]
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Hands-On AOP Seminar at SOT: Creating an Adverse Outcome Pathway in the AOP Wiki

Contributor: Marilyn Matevia, HSUS (Reposted from the January AltTox Digest) The Human Toxicology Project Consortium (HTPC) and the Physicians Committee for Responsible Medicine (PCRM) will co-sponsor a “hands-on seminar,” Creating an Adverse Outcome Pathway in the AOP Wiki, Tuesday, March 15 from 5:00 PM–7:00 PM in the Belle Chasse Room of the Hilton New Orleans […]
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ASCCT Webinar: Integrating In Silico Predictions with Physiologically Based Pharmacokinetic (PBPK) Modeling

Contributor: Marilyn Matevia, HSUS You can still register for ASCCT’s upcoming webinar on Integrating In Silico Predictions with Physiologically Based Pharmacokinetic (PBPK) Modeling, being presented this coming Monday, Feb 29, 2016 at 2:00 PM EST. Because of high demand, the organizers have added capacity and they encourage registrations: https://attendee.gotowebinar.com/register/4614615489276420098 The webinar will cover two applications […]
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Good Read-Across Practice (GRAP) Guidance Workshop

Contributor: Kate Willett, HSUS March 1, 2016 10am – 4pm US Food and Drug Administration (FDA) Center for Food Safety and Applied Nutrition Wiley Building 1A003 CFSAN Auditorium 5100 Paint Branch Parkway College Park, MD 20740 Co-hosted by the US Food and Drug Administration Center for Food Safety and Advanced Nutrition (FDA-CFSAN) and the Center […]
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IVAM webinar recordings now available: Using IATA to Facilitate Regulatory Use of Non-Standard Testing Methods

Contributor: Marilyn Matevia, HSUS A recording of the January 27 SOT In Vitro and Alternative Methods Specialty Section webinar, “Use of Integrated Approaches to Testing and Assessment (IATA) To Facilitate Regulatory Use of Non-Standard Testing Methods,” is now available here. The webinar featured two presentations: Introduction to the concept of Adverse Outcome Pathways and IATA […]
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Jan 27 Webinar on using Integrated Approaches to Testing and Assessment (IATA) To Facilitate Regulatory Use of Non-Standard Testing Methods

Contributor: Marilyn Matevia, HSUS The SOT In Vitro and Alternative Methods Specialty Section will host a webinar on Use of Integrated Approaches to Testing and Assessment (IATA) To Facilitate Regulatory Use of Non-Standard Testing Methods on Wednesday, Jan. 27, at 12:00 p.m. Eastern Time. Catherine Willett, Ph.D., of the Humane Society of the United States […]
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Job Opening: Science Communications Officer, HSI/HSUS

Contributor: Marilyn Matevia, HSUS The Humane Society family of organizations (The Humane Society of the United States/HSUS and Humane Society International/HSI) is looking for a Science Communications Officer to advance HSI/HSUS global efforts to stimulate a shift in bioscience research and drug discovery toward human biology-based technologies and models for safety, efficacy and human disease; […]
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Federal Agencies Launch the Transform Tox Testing Challenge to Improve Chemical Screening

Contributor: Marilyn Matevia, HSUS Press release from the EPA, announcing a team challenge to “find new ways to incorporate physiological levels of chemical metabolism into HTS assays”: Today, the U.S. Environmental Protection Agency (EPA) and the National Institutes of Health’s (NIH) National Center for Advancing Translational Sciences (NCATS), and NIH’s National Toxicology Program (NTP) within […]
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The Hamner Institutes for Health Sciences has closed

Contributor: Marilyn Matevia, HSUS A news item in the Triangle Business Journal announces that the Hamner Institutes for Health Sciences has closed. The article notes that a local health consulting company, SciMetrika, has acquired the assets of one Hamner division, the Institute for Chemical Safety Sciences (ICSS), and will “house” these in ScitoVation, “a wholly […]
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PCRM Job Opportunity: Director of Research Policy

Contributor: Ashley Felder, PCRM The Physicians Committee for Responsible Medicine is looking for a director with a background in medicine or the life sciences, a passion for animal welfare, and strong leadership and communication skills. The Director of Research Policy will develop and implement strategies to save human and animal lives by replacing the use […]
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UK “roadmap” to wider use of non-animal technologies

Contributor: Marilyn Matevia, HSUS Six organizations, including NC3Rs, have published a “roadmap” to facilitate the UK’s development and embrace of non-animal technologies, Advancing Predictive Biology. In a recent blog post, NC3Rs Chief Executive Dr. Vicky Robinson provides context to the project: The roadmap is part of a wider collaboration between the six partners which has […]
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Job openings at Silent Spring Institute

Contributor: Kate Willett, HSUS The Silent Spring Institute is looking for research scientists in data science and informatics, chemistry/biochemistry and biomonitoring, and molecular biology or endocrinology. The Institute is seeking candidates for three position postings: a versatile data scientist, machine learning expert, or statistician to tackle big data problems in environmental health and breast cancer […]
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Upcoming workshop: Environment and Health – What’s the Human Microbiome Have to Do With It?

Contributor: Solmaz Spence, National Academies of Sciences, Engineering, and Medicine Workshop Title: The National Academies of Sciences, Engineering, and Medicine’s Emerging Science for Environmental Health Decisions Workshop, Environment and Health: What’s the Human Microbiome Have to Do With It? Date: January 14-15 2016 Location: Washington, D.C., and via webcast The microbiome—the collection of bacteria, viruses […]
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ARDF announces recipients of the 2015 Alternatives Research Grant Program awards

Contributor: Sue A. Leary, Alternatives Research & Development Foundation (ARDF) ARDF is pleased to announce that its 2015 Alternatives Research Grant Program has made its selections. ARDF has awarded $220,000 to scientists developing alternative methods in a variety of areas of medical research, testing, and education. Congratulations to awardees: April Davis, PhD and William Lee, […]
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New paper describes improved method for quantifying electrophiles (potential skin sensitizers)

Contributor: Amar G. Chittiboyina, PhD, National Center for Natural Product Research To add structural information to the existing in chemico methods, an NMR-based method is proposed for probing the reactivity and classification of the potential electrophiles (E) using a model thiol, DCYA. The major advantage of the NMR method is the quantitation of the actual […]
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ASCCT offering student travel awards for the 17th International Conference on QSAR in Environmental and Health Sciences

Contributor: Kristie Sullivan, PCRM The 17th International Conference on QSAR in Environmental and Health Sciences takes place June 13-17, 2016, in Miami Beach, Florida. The abstract deadline is December 4, 2015; early bird registration ends March 1, 2016. Since 1983, this meeting has been an important international gathering in the field of Environmental and Health […]
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Scientific Job Openings with PETA US and PETA UK

Contributor: Katherine Groff, PETA International Science Consortium Ltd. Multiple scientific positions are available in PETA US and UK offices (check out all of the positions here: http://www.piscltd.org.uk/employment-opportunities-with-peta-us-and-peta-uk), including a Corporate Liaison position in the Regulatory Testing Department with PETA US. The Corporate Liaison will oversee, develop, and carry out PETA’s work with major corporations to […]
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New publication on non-animal affinity reagents

Contributor: Amy J. Clippinger, PETA International Science Consortium Ltd. There is a growing concern about the lack of quality and reproducibility of animal-derived antibodies, which often show poor specificity or fail to recognize their targets. Time, money, and tens of thousands of animals could be saved, while improving the reproducibility of research, by replacing animal-derived […]
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EPA’s Advancing Systematic Review Workshop (Dec 16-17): Expert/Topic Nominations due November 5

Contributor: Marilyn Matevia, HSUS The US EPA’s National Center for Environmental Assessment (NCEA) is now accepting nominations for experts and topics for its December 16-17 workshop, Advancing Systematic Review for Chemical Risk Assessment. Nominations are due November 5. From the EPA’s meeting announcement: “EPA is developing and implementing a systematic review process within the IRIS […]
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