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If you are attending the Society of Toxicology’s annual meeting in Baltimore next month, the Human Toxicology Project Consortium (HTPC) and the Physicians Committee for Responsible Medicine (PCRM) invite you to deepen your understanding of the AOP Wiki and gain experience entering an Adverse Outcome Pathway in a structured, hands-on seminar Tuesday evening, March 14. […]

If you’re planning to attend the Society of Toxicology conference in Baltimore this March, please join the Center for Alternatives to Animal Testing (CAAT), the Human Toxicology Project Consortium (HTPC), and the Human Toxome Project Consortium for the annual satellite meeting on 21st century toxicology activities and related efforts, Thursday, March 16 from noon to […]

As in previous years, AltTox Editorial Board and Management Team members will be at the annual meeting of the Society of Toxicology (Baltimore, Maryland) to share research with thousands of other toxicologists. AltTox Editorial Board and/or Management Team members are co-authors of the following posters (listed by abstract #/poster board #): 1209/333: Systematic Reviews as […]

Laura Henning, IIVS The Institute for In Vitro Sciences (IIVS) is proud to announce its 20th anniversary as an international leader in the in vitro (non-animal) testing field. Founded in 1997, IIVS is unique in its position as a high quality testing laboratory while also offering technical and educational resources to increase the use and […]

Sonja von Aulock, ALTEX Scientists from the European Chemicals Agency (ECHA) around Andrea Gissi and Kimmo Louekari have published an analysis of data in the REACH registration database that supports the use of sub-acute toxicity results, together with other relevant information, to cover the acute toxicity standard requirements for REACH registration in a weight of […]

Francois Busquet, CAAT Academy The CAAT Academy training program for 2017 has been published. The following sessions will be offered: Organs-on-a-chip @MIMETAS, Leiden (NL) In vitro skin & eye models – Part 1 @VUB, Brussels (BE) Liver models and AOP @Biopredic International, Rennes (FR) EDC in vitro models @Biodetection Systems, Amsterdam (NL) ADME @KUL, Leuven […]

Katherine Groff, PETA International Science Consortium Ltd. PETA’s Regulatory Testing Department is seeking a Corporate Liaison to join its growing team. This person will work with major corporations to replace and reduce animal testing. A successful candidate will attend corporate meetings and scientific conferences and maintain expertise in nonanimal test methods and international regulatory requirements. […]

Francois Busquet, CAAT Dates: September 22-23, 2016 Location: Vienna, Austria, Evercyte Laboratories This 2-days training will give a comprehensive overview of the most relevant and robust 2D and 3D kidney cell culture models and in vitro applications for the assessment of kidney-associated cytotoxicity. Webinar will be available during the training but for the presentations only. […]

Kate Willett, HSUS The OECD has published a Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests. From the introduction: The OECD Guidelines for the Testing of Chemicals are continually evolving to reflect changing assessment practices. Acute toxicity tests are an area of focus for developing alternative assays to address animal […]

Contributor: Pascaline Clerc, HSUS Deadline for preproposals: May 16, 2016 The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) is soliciting projects that focus on the implementation of the NAS Report, Toxicity Testing in the 21st Century: A Vision and a Strategy in the following areas: Proposals Relating to Toxicology: Maximum grant amount is […]

Introduction Nanotechnology encompasses a wide variety of nanosized materials, or nanomaterials (NMs), which are defined by the International Organization for Standardization (ISO) as materials with any external dimension in the nanoscale or having internal structure or surface structure in the nanoscale (ISO, 2011). There is a large number of NMs in the global marketplace with […]

Contributor: Marilyn Matevia, HSUS An announcement from the Society of Environmental Toxicology and Chemistry (SETAC): “The Society for Environmental Toxicology and Chemistry (SETAC) is initiating a horizon scanning effort to advance the science and application of the Adverse Outcome Pathway (AOP) framework. This horizon scanning approach will allow us to identify and begin to address […]

Contributor: Marilyn Matevia, HSUS The AltTox.org team will be at the annual Society of Toxicology meeting in New Orleans next week, sharing an informational booth with our site co-sponsor, the Human Toxicology Project Consortium. If you are planning to be there, please stop by booth #1704 to say hello and enter our t-shirt raffle! A […]

Contributor: Marilyn Matevia, HSUS (Reposted from the January AltTox Digest) The Human Toxicology Project Consortium (HTPC) and the Physicians Committee for Responsible Medicine (PCRM) will co-sponsor a “hands-on seminar,” Creating an Adverse Outcome Pathway in the AOP Wiki, Tuesday, March 15 from 5:00 PM–7:00 PM in the Belle Chasse Room of the Hilton New Orleans […]

Contributor: Marilyn Matevia, HSUS You can still register for ASCCT’s upcoming webinar on Integrating In Silico Predictions with Physiologically Based Pharmacokinetic (PBPK) Modeling, being presented this coming Monday, Feb 29, 2016 at 2:00 PM EST. Because of high demand, the organizers have added capacity and they encourage registrations: https://attendee.gotowebinar.com/register/4614615489276420098 The webinar will cover two applications […]

Contributor: Kate Willett, HSUS March 1, 2016 10am – 4pm US Food and Drug Administration (FDA) Center for Food Safety and Applied Nutrition Wiley Building 1A003 CFSAN Auditorium 5100 Paint Branch Parkway College Park, MD 20740 Co-hosted by the US Food and Drug Administration Center for Food Safety and Advanced Nutrition (FDA-CFSAN) and the Center […]

Contributor: Marilyn Matevia, HSUS A recording of the January 27 SOT In Vitro and Alternative Methods Specialty Section webinar, “Use of Integrated Approaches to Testing and Assessment (IATA) To Facilitate Regulatory Use of Non-Standard Testing Methods,” is now available here. The webinar featured two presentations: Introduction to the concept of Adverse Outcome Pathways and IATA […]

Contributor: Marilyn Matevia, HSUS The SOT In Vitro and Alternative Methods Specialty Section will host a webinar on Use of Integrated Approaches to Testing and Assessment (IATA) To Facilitate Regulatory Use of Non-Standard Testing Methods on Wednesday, Jan. 27, at 12:00 p.m. Eastern Time. Catherine Willett, Ph.D., of the Humane Society of the United States […]

Contributor: Marilyn Matevia, HSUS The Humane Society family of organizations (The Humane Society of the United States/HSUS and Humane Society International/HSI) is looking for a Science Communications Officer to advance HSI/HSUS global efforts to stimulate a shift in bioscience research and drug discovery toward human biology-based technologies and models for safety, efficacy and human disease; […]

Contributor: Marilyn Matevia, HSUS Press release from the EPA, announcing a team challenge to “find new ways to incorporate physiological levels of chemical metabolism into HTS assays”: Today, the U.S. Environmental Protection Agency (EPA) and the National Institutes of Health’s (NIH) National Center for Advancing Translational Sciences (NCATS), and NIH’s National Toxicology Program (NTP) within […]

Contributor: Marilyn Matevia, HSUS A news item in the Triangle Business Journal announces that the Hamner Institutes for Health Sciences has closed. The article notes that a local health consulting company, SciMetrika, has acquired the assets of one Hamner division, the Institute for Chemical Safety Sciences (ICSS), and will “house” these in ScitoVation, “a wholly […]

Contributor: Ashley Felder, PCRM The Physicians Committee for Responsible Medicine is looking for a director with a background in medicine or the life sciences, a passion for animal welfare, and strong leadership and communication skills. The Director of Research Policy will develop and implement strategies to save human and animal lives by replacing the use […]

Contributor: Marilyn Matevia, HSUS Six organizations, including NC3Rs, have published a “roadmap” to facilitate the UK’s development and embrace of non-animal technologies, Advancing Predictive Biology. In a recent blog post, NC3Rs Chief Executive Dr. Vicky Robinson provides context to the project: The roadmap is part of a wider collaboration between the six partners which has […]

Contributor: Kate Willett, HSUS The Silent Spring Institute is looking for research scientists in data science and informatics, chemistry/biochemistry and biomonitoring, and molecular biology or endocrinology. The Institute is seeking candidates for three position postings: a versatile data scientist, machine learning expert, or statistician to tackle big data problems in environmental health and breast cancer […]

Contributor: Solmaz Spence, National Academies of Sciences, Engineering, and Medicine Workshop Title: The National Academies of Sciences, Engineering, and Medicine’s Emerging Science for Environmental Health Decisions Workshop, Environment and Health: What’s the Human Microbiome Have to Do With It? Date: January 14-15 2016 Location: Washington, D.C., and via webcast The microbiome—the collection of bacteria, viruses […]

Contributor: Sue A. Leary, Alternatives Research & Development Foundation (ARDF) ARDF is pleased to announce that its 2015 Alternatives Research Grant Program has made its selections. ARDF has awarded $220,000 to scientists developing alternative methods in a variety of areas of medical research, testing, and education. Congratulations to awardees: April Davis, PhD and William Lee, […]

Contributor: Amar G. Chittiboyina, PhD, National Center for Natural Product Research To add structural information to the existing in chemico methods, an NMR-based method is proposed for probing the reactivity and classification of the potential electrophiles (E) using a model thiol, DCYA. The major advantage of the NMR method is the quantitation of the actual […]

Contributor: Kristie Sullivan, PCRM The 17th International Conference on QSAR in Environmental and Health Sciences takes place June 13-17, 2016, in Miami Beach, Florida. The abstract deadline is December 4, 2015; early bird registration ends March 1, 2016. Since 1983, this meeting has been an important international gathering in the field of Environmental and Health […]

Contributor: Marilyn Matevia, HSUS AltTox visitors might experience a very brief outage on the site tomorrow, November 10, at some point between the hours of 7:00 AM GMT (or 1:00 AM Central US time) and 12:00 PM GMT (6:00 AM Central). This is due to scheduled site maintenance. If any disruption occurs, it will be […]

Contributor: Katherine Groff, PETA International Science Consortium Ltd. Multiple scientific positions are available in PETA US and UK offices (check out all of the positions here: http://www.piscltd.org.uk/employment-opportunities-with-peta-us-and-peta-uk), including a Corporate Liaison position in the Regulatory Testing Department with PETA US. The Corporate Liaison will oversee, develop, and carry out PETA’s work with major corporations to […]

Contributor: Amy J. Clippinger, PETA International Science Consortium Ltd. There is a growing concern about the lack of quality and reproducibility of animal-derived antibodies, which often show poor specificity or fail to recognize their targets. Time, money, and tens of thousands of animals could be saved, while improving the reproducibility of research, by replacing animal-derived […]