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Monthly Archive for: "December, 2017"
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ICCVAM Communities of Practice Webinar January 23

The fourth ICCVAM Communities of Practice webinar will be presented January 23, 2018, on the topic “Machine Learning in Toxicology: Fundamentals of Application and Interpretation.” NICEATM is organizing this webinar on behalf of ICCVAM. This webinar will explore the fundamentals of machine learning approaches, including how they work, how they are interpreted, and precautions that […]
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Grants Offer Support for Tissue Chip Development

The National Institutes of Health (NIH) has announced several funding opportunities for research and development of microphysiological systems (MPS; “tissue chips”) for studying human physiology and assessing toxicity and safety of new drugs and other substances. All of these funding opportunities are open to U.S.-based for-profit, non-profit, academic, and government institutions. NIH is offering 1-2 […]
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USDA Releases Guidance Documents on Animal Health

The U.S. Department of Agriculture (USDA) administers the Animal Welfare Act, which sets standards for the humane care and treatment of animals used in research. USDA Animal Care has developed two Tech Notes for Animal Welfare Act licensees and registrants to help improve adherence to animal welfare standards. “Incentives for Identifying, Reporting, Correcting, and Preventing […]
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National Academies of Sciences Workshop on “The Promise of Genome Editing Tools to Advance Environmental Health Research” Begins on January 10

Recent scientific advances have made genome editing technologies—a suite of biological tools for making precise additions, deletions, and alterations to the DNA and RNA of living cells– more rapid, efficient, and flexible than ever before. Join experts in molecular biology, toxicology, and public health to explore opportunities for using genome (and epigenome) editing technologies in […]
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EPA Requests Nominees for Scientific Advisory Panel

EPA is seeking nominations of ad hoc members for its Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP). The FIFRA SAP will meet in 2018 to consider physiologically based pharmaokinetic models to address species differences in pharmacokinetics for pesticide active ingredients. The request for nominees was published in a December 18 Federal […]
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IVIVE Workshop Report Available

A manuscript summarizing a February 2016 workshop, In Vitro to In Vivo Extrapolation for High Throughput Prioritization and Decision Making, and a preceding webinar series was published online December 5 by the journal Toxicology In Vitro. The manuscript is available on the journal’s website. The workshop report discusses activities and resources that promote inclusion of […]
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NIDDK Offers Support for Development of Tissue Chips

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is establishing a new research consortium “Microphysiological Systems for Modeling Diabetes.” This consortium will support the development and validation of human tissue chips that closely mimic the normal physiology of key metabolic tissues, including the pancreatic islet, liver, skeletal muscle, and white adipose tissue. […]
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EURL ECVAM Status Report 2017 on alternative methods now available

EURL ECVAM Status Report on the Development, Validation and Regulatory Acceptance of Alternative Methods and Approaches (2017) Download here: http://publications.jrc.ec.europa.eu/repository/handle/JRC108831 “Every year, EURL ECVAM prepares a Status Report with the primary purpose to inform its stakeholders … on updates on the status of alternative methods and approaches. The [2017] EURL ECVAM status report provides updates […]
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Informational Webinar on Tissue Chip Grants December 14

The Center for the Advancement of Science in Space (CASIS) has partnered with the National Institutes of Health (NIH) and the National Science Foundation (NSF) to fund new opportunities for conducting research onboard the International Space Station. The NIH-CASIS Coordinated Microphysiological Systems Program for Translational Research in Space promotes the development of tissue chips to […]
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Proposals for Organotypic Culture Models Due December 12

The National Institute of Environmental Health Sciences (NIEHS) is offering Small Business Innovation Research (SBIR) grants to develop novel in vitro systems using cells from experimental animal models typically used for toxicology testing. The intent is that these systems will replicate biological responses within the corresponding animal tissues or organs. When developed and validated, these […]
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Journal to Focus on Inhalation Toxicity: Submit Articles by December 15

The journal Applied In Vitro Toxicology is accepting manuscript submissions for a special issue on alternative approaches for inhalation toxicity testing. Submissions must be received by December 15. Inhalation toxicity testing provides information for hazard labeling and risk management of chemicals when there is potential for exposure of the respiratory tract. Regulatory test guidelines typically […]
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FDA Launches Predictive Toxicology Roadmap

In an article published December 6 on the FDA Voice blog, the U.S. Food and Drug Administration (FDA) announced publication of FDA’s Predictive Toxicology Roadmap for integrating predictive toxicology methods into safety and risk assessments. The Predictive Toxicology Roadmap presents a framework for new or enhanced FDA engagement in the science of toxicology that includes […]
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EPA Webinar on Steroidogenesis Assay December 14

The U.S. Environmental Protection Agency (EPA) will present a webinar titled “High-Throughput H295R Steroidogenesis Assay: Utility as an Alternative and a Statistical Approach to Characterize Effects on Steroidogenesis” on Thursday, December 14, from 11:00 a.m.-noon U.S. Eastern Time. The speaker is Dr. Derik Haggard, ORISE Postdoctoral Fellow with the EPA National Center for Computational Toxicology. […]
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HESI’s Emerging Issues Proposal Solicitation

ILSI’s Health and Environmental Sciences Institute (HESI) seeks your suggestions for priority emerging scientific issues (human or environmental health) that should be addressed through a focused, multi-sector collaborative program. One or more of the proposals will be selected to from a new scientific collaborative program within HESI. This is not a grant program and no […]
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