Posted: April 25, 2016 Around 10,000 different proteins have been identified in each of eleven examined human cell lines (Beck et al., 2011; Geiger et al., 2012). These cellular proteins are not sloshing around in a chaotic fashion, but are highly organized into sub-cellular domains or compartments, and their activities are part of one or […]
Contributor: Sherry Ward, AltTox Source: USDA Animal and Plant Health Inspection Service Weekly Digest Bulletin, 04/19/2016 Dear RCC stakeholders: We invite you to participate in the U.S.–Canada Regulatory Cooperation Council Stakeholder Meeting, to be held at the Embassy of Canada in Washington, D.C. on May 4-5 2016. Please indicate your attendance at this two-day event […]
The publication of a study by Coleman and colleagues (2015) that evaluates the SenCeeToxTM as a possible in vitro alternative for assessing skin sensitization in medical devices was recently named “Best Published Paper” by the Society of Toxicology Medical Device Specialty Section. Skin sensitization tests are among the tests recommended by regulatory agencies, such as […]
Contributor: Sherry Ward, AltTox Science for Environment Policy, a free news and information service published by Directorate-General Environment, European Commission, has published two new reports as part of their work to support policymakers with “quality environmental research for evidence-based policy.” Identifying emerging risks for environmental policies. Future Brief 13: “While identifying, predicting and monitoring known […]
Contributor: Sherry Ward, AltTox Tools for Cell Line Identification (SBIR [R43/R44]); PA-16-186 Due Dates: Standard dates through April 6, 2019 Funding Opportunity Purpose: This Funding Opportunity Announcement (FOA) is intended to address the problem of misidentified cell lines. Many advances in biomedical science have arisen from studies of cultured cell lines, which are widely used […]
Contributor: Sherry Ward, AltTox Source: ACI e-newsletter The second in a series of ACI-sponsored webinars exploring the science behind chemical-induced asthma will be held Thursday, April 28 at 2:00 p.m. ET. The session will feature a presentation by Dr. David Basketter on “The Role of Toxicology in Asthma Hazard Assessment.” Dr. Basketter is a Eurotox […]
Contributor: Sherry Ward, AltTox The FDA has released a number of new funding opportunities, some with the potential for development or use of human clinical and/or in vitro methodologies. Part of one of the funding announcements is shown below. The full list of funding announcements is provided on this webpage: FY2016 GDUFA Regulatory Science Funding […]
Introduction Nanotechnology encompasses a wide variety of nanosized materials, or nanomaterials (NMs), which are defined by the International Organization for Standardization (ISO) as materials with any external dimension in the nanoscale or having internal structure or surface structure in the nanoscale (ISO, 2011). There is a large number of NMs in the global marketplace with […]
Contributor: Sherry Ward, AltTox Source: European Pharmacopoeia Work Programme Symposium 10 May 2016 to 11 May 2016; Oslo, Norway Programme Overview Global production of fish from aquaculture has grown substantially in the past decade and this growth has brought with it many economic benefits and challenges. Like other forms of animal production, disease prevention and […]
Contributor: Sherry Ward, AltTox Source: European Pharmacopoeia News 10 March 2016 As part of the Ph. Eur. Commission’s efforts to replace in vivo with in vitro methods, around 40 inactivated vaccine-specific monographs and the general monograph Vaccines for veterinary use (0062) were adopted at its 153rd Session in November 2015. These texts will be published […]
Contributor: Catherine Sprankle, NICEATM ICCVAM will hold a public forum on Wednesday, May 25, 2016, from 9:00 a.m. to approximately 4:00 p.m. at the National Institutes of Health Natcher Conference Center in Bethesda, Maryland. Representatives of the federal agencies on ICCVAM will be present to hear ideas and suggestions from interested stakeholders and the public. […]
