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Monthly Archive for: "July, 2015"
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ECHA follows up on registrants’ obligations to consider alternative tests

Contributor: Sherry Ward, AltTox Source: ECHA News http://echa.europa.eu/view-article/-/journal_content/title/echa-follows-up-on-registrants-obligations-to-consider-alternative-tests ECHA has analysed why registrants submitted 295 new higher tier studies on vertebrate animals without first seeking the Agency’s decision to permit such tests. In general, registrants were able to clarify why the new studies were conducted and submitted for registration purposes. However, in a number of cases […]
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Chemical Aquatic Fate and Effects (CAFE) Database released by NOAA

Contributor: Sherry Ward, AltTox Sources: ECETOC (http://www.ecetoc.org/index.php?mact=Newsroom,cntnt01,details,0&cntnt01documentid=285&cntnt01returnid=76) and NOAA (http://response.restoration.noaa.gov/cafe) The Chemical Aquatic Fate and Effects (CAFE) database (http://response.restoration.noaa.gov/oil-and-chemical-spills/chemical-spills/response-tools/download-install-and-run-cafe.html) is a software program you can use to estimate the fate and effects of thousands of chemicals, oils, and dispersants. CAFE serves as a tool to help responders in their assessment of environmental impacts from chemical […]
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The 3Rs-Centre Utrecht Life Sciences continues NKCA activities

Contributor: Jan van der Valk, 3Rs Centre-Utrech Life Sciences For 4 years (2010-2014) the Netherlands Knowledge Centre on Alternatives (NKCA) was responsible for promoting the application of the 3R-alternatives – replacement, reduction and refinement – in the Netherlands. The Centre, which was a collaboration between the RIVM and the Utrecht University, was established by the […]
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Preclinical Assays Needed to Predict Vaccine Efficacy

Contributor: Sherry Ward, AltTox Source: http://www.niaid.nih.gov/researchfunding/newsletter/2015/Pages/0715.aspx#or02 Promising preclinical data for a candidate vaccine does not guarantee efficacy in phase II/III clinical trials. Thus, NIAID seeks novel preclinical assays capable of better predicting the likelihood of success in human clinical studies based on preclinical outcomes. As researchers continue to identify new potential markers of protection, new […]
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NIEHS Offers Financial Support for Later Stages of Test Method Development

Contributor: Catherine Sprankle, NICEATM The National Institute of Environmental Health Sciences (NIEHS) will provide additional support to current federal grantees for validation and commercialization of replacement or reduction alternatives to tests required by U.S. government agencies. These Small Business Innovation Research (SBIR) Phase IIB awards will support further development of non-clinical toxicology tests for use […]
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Open position at PCRM: Science Policy Specialist

Contributor: Kristie Sullivan, PCRM The Physicians Committee is looking for a Science Policy Specialist to join our team. The ideal candidate for this position will have a basic knowledge of toxicological and pharmacological concepts including in vivo, in vitro, and in silico test methods and familiarity with the laws, regulations, and practices related to efficacy […]
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Introduction to Complexity – free, online course starts today

Contributor: Sherry Ward, AltTox The free and online course by the Santa Fe Institute, “Introduction to Complexity” (http://www.complexityexplorer.org), begins today. The purpose of this course is to help registrants learn about the tools used by scientists to understand complex systems. This is an introductory course and there are no math or other prerequisites. To see […]
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NIH Announces Strategy to Improve Reproducibility of Funded Research

Contributor: Sherry Ward, AltTox Source: http://www.niaid.nih.gov/researchfunding/newsletter/2015/Pages/0701.aspx#itn01 “In an effort to advance the highest level of scientific integrity, NIH has unveiled a strategy to improve the reproducibility of the research it funds in two June 9, 2015 Guide notices: Enhancing Reproducibility Through Rigor and Transparency and Consideration of Sex as a Biological Variable in NIH-Funded Research. […]
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